CHEBI:139326 - methoxypoly(ethylene glycol)-maleimide

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ChEBI Name methoxypoly(ethylene glycol)-maleimide
ChEBI ID CHEBI:139326
Definition A poly(ethylene glycol) derivative that is methoxypoly(ethylene glycol) in which the terminal hydroxy group has been converted to the corresponding 2-maleimidoethyl ether. Used particularly for the mPEGylation of free thiol groups in cysteine residues of proteins.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula (C2H4O)n.C5H5NO2
Net Charge 0
Roles Classification
Application(s): reagent
A substance used in a chemical reaction to detect, measure, examine, or produce other substances.
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ChEBI Ontology
Outgoing methoxypoly(ethylene glycol)-maleimide (CHEBI:139326) has role reagent (CHEBI:33893)
methoxypoly(ethylene glycol)-maleimide (CHEBI:139326) is a maleimides (CHEBI:55417)
methoxypoly(ethylene glycol)-maleimide (CHEBI:139326) is a poly(ethylene glycol) derivative (CHEBI:139322)
IUPAC Name
α-methyl-ω-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)poly(oxyethylene)
Synonyms Sources
methoxy-polyethylene glycol maleimide ChEBI
mono-methyl poly(ethylene glycol) 2-maleimidoethyl ether ChEBI
monomethoxypoly(ethylene glycol)-maleimide ChEBI
mPEG-MAL ChEBI
mPEG-maleimide ChEBI
Registry Numbers Types Sources
15366089 Reaxys Registry Number Reaxys
99126-64-4 CAS Registry Number ChEBI
Citations Waiting for Citations Types Sources
23981355 PubMed citation Europe PMC
25667612 PubMed citation Europe PMC
25918947 PubMed citation Europe PMC
27355203 PubMed citation Europe PMC
28497240 PubMed citation Europe PMC
29053917 PubMed citation Europe PMC
Last Modified
19 December 2017