CHEBI:133234 - quininib hydrochloride

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ChEBI Name quininib hydrochloride
ChEBI ID CHEBI:133234
Definition A hydrochloride salt resulting from the formal reaction of equimolar amounts of quininib and hydrogen chloride. It is an anti-angiogenic compound that exerts a dose-dependent antagonism of the cysteinyl leukotriene pathway, preferentially antagonising cysteinyl leukotriene receptor 1.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C17H14ClNO
Net Charge 0
Average Mass 283.753
Monoisotopic Mass 283.07639
InChI InChI=1S/C17H13NO.ClH/c19-17-8-4-2-6-14(17)10-12-15-11-9-13-5-1-3-7-16(13)18-15;/h1-12,19H;1H/b12-10+;
InChIKey OGGHGIYQZSZPJX-VHPXAQPISA-N
SMILES C1=2C(C=CC=C1)=NC(=CC2)/C=C/C=3C(=CC=CC3)O.Cl
Roles Classification
Application(s): angiogenesis inhibitor
An agent and endogenous substances that antagonize or inhibit the development of new blood vessels.
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ChEBI Ontology
Outgoing quininib hydrochloride (CHEBI:133234) has part quininib(1+) (CHEBI:133233)
quininib hydrochloride (CHEBI:133234) has role angiogenesis inhibitor (CHEBI:48422)
quininib hydrochloride (CHEBI:133234) is a hydrochloride (CHEBI:36807)
IUPAC Names
2-[(E)-2-(2-hydroxyphenyl)vinyl]quinolinium chloride
2-[(E)-2-(quinolin-2-yl)vinyl]phenol hydrochloride
Synonym Source
quininib.HCl ChEBI
Last Modified
11 September 2016