1,3,6,8-tetraazatricyclo[6.2.1.1(3,6)]dodecane (CHEBI:63487)

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ChEBI Name	1,3,6,8-tetraazatricyclo[6.2.1.1^3,6]dodecane

ChEBI ID	CHEBI:63487

ChEBI ASCII Name	1,3,6,8-tetraazatricyclo[6.2.1.1(3,6)]dodecane

Definition	An azatricycloalkane that is tricyclo[6.2.1.1^3,6]dodecane in which the four bridgehead CH groups are replaced by nitrogen atoms. It is a small-molecule BAX agonist.

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

Download	Molfile XML SDF

Formula

C8H16N4

Net Charge

Average Mass

168.23940

Monoisotopic Mass

168.13750

InChI

InChI=1S/C8H16N4/c1-2-10-5-9(1)7-11-3-4-12(6-11)8-10/h1-8H2

InChIKey

ZBFHXDNNFOOFLY-UHFFFAOYSA-N

SMILES

C1CN2CN1CN1CCN(C2)C1

Roles Classification
Chemical Role(s):	Bronsted base A molecular entity capable of accepting a hydron from a donor (Bronsted acid). (via organic amino compound )

Biological Role(s):	apoptosis inducer Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.

Application(s):	antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms.

ChEBI Ontology
Outgoing	1,3,6,8-tetraazatricyclo[6.2.1.1^3,6]dodecane (CHEBI:63487) has role antineoplastic agent (CHEBI:35610) 1,3,6,8-tetraazatricyclo[6.2.1.1^3,6]dodecane (CHEBI:63487) has role apoptosis inducer (CHEBI:68495) 1,3,6,8-tetraazatricyclo[6.2.1.1^3,6]dodecane (CHEBI:63487) is a azatricycloalkane (CHEBI:63489) 1,3,6,8-tetraazatricyclo[6.2.1.1^3,6]dodecane (CHEBI:63487) is a bridged compound (CHEBI:35990) 1,3,6,8-tetraazatricyclo[6.2.1.1^3,6]dodecane (CHEBI:63487) is a tetramine (CHEBI:39166)

IUPAC Name

1,3,6,8-tetraazatricyclo[6.2.1.1^3,6]dodecane

Synonyms	Sources
1,3,6,8-diendomethylene-1,3,6,8-tetraazacyclodecane	ChEBI
1,3,6,8-tetraazatricyclo[6.2.1.1(3,6)]dodecane	ChEBI
1,3,6,8-tetraazatricyclo[6.2.1.13,6]dodecane	ChemIDplus
NSC 4436	ChemIDplus
SMBA2	ChEBI

Brand Name	Source
Dimtac	ChEBI

Last Modified

13 May 2021