CHEBI:31762 - lanperisone hydrochloride

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ChEBI Name lanperisone hydrochloride
ChEBI ID CHEBI:31762
Definition The hydrochloride salt of lanperisone. It is a muscle relaxant.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C15H18F3NO.ClH
Net Charge 0
Average Mass 321.770
Monoisotopic Mass 321.11073
InChI InChI=1S/C15H18F3NO.ClH/c1-11(10-19-8-2-3-9-19)14(20)12-4-6-13(7-5-12)15(16,17)18;/h4-7,11H,2-3,8-10H2,1H3;1H/t11-;/m1./s1
InChIKey PHBZFPOOJUGYCR-RFVHGSKJSA-N
SMILES Cl.C[C@H](CN1CCCC1)C(=O)C1=CC=C(C=C1)C(F)(F)F
Roles Classification
Biological Role(s): ferroptosis inducer
Any substance that induces or promotes ferroptosis (a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides) in organisms.
voltage-gated sodium channel blocker
Any sodium channel blocker that interferes with the activity of voltage-gated sodium channels.
calcium channel blocker
One of a class of drugs that acts by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools.
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
muscle relaxant
A drug used to produce muscle relaxation (excepting neuromuscular blocking agents). Its primary clinical and therapeutic use is the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. Also used for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in multiple sclerosis.
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ChEBI Ontology
Outgoing lanperisone hydrochloride (CHEBI:31762) has part lanperisone(1+) (CHEBI:176341)
lanperisone hydrochloride (CHEBI:31762) has role antineoplastic agent (CHEBI:35610)
lanperisone hydrochloride (CHEBI:31762) has role calcium channel blocker (CHEBI:38215)
lanperisone hydrochloride (CHEBI:31762) has role ferroptosis inducer (CHEBI:173085)
lanperisone hydrochloride (CHEBI:31762) has role muscle relaxant (CHEBI:51371)
lanperisone hydrochloride (CHEBI:31762) has role voltage-gated sodium channel blocker (CHEBI:38634)
lanperisone hydrochloride (CHEBI:31762) is a hydrochloride (CHEBI:36807)
IUPAC Name
(2R)-2-methyl-3-(pyrrolidin-1-yl)-1-[4-(trifluoromethyl)phenyl]propan-1-one hydrochloride
Synonyms Sources
(−)-(R)-2-methyl-3-(1-pyrrolidinyl)-4'-trifluoromethylpropiophenone monohydrochloride ChEBI
1-{(2R)-2-methyl-3-oxo-3-[4-(trifluoromethyl)phenyl]propyl}pyrrolidinium chloride IUPAC
lanperisone HCl ChEBI
Lanperisone hydrochloride KEGG DRUG
lanperisone monohydrochloride ChEBI
NK 433 KEGG DRUG
NK-433 ChEBI
NK433 ChEBI
Manual Xrefs Databases
171990 ChemSpider
C13320 KEGG COMPOUND
D01848 KEGG DRUG
EP0770386 Patent
View more database links
Registry Number Type Source
116287-13-9 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
16126840 PubMed citation Europe PMC
7737318 PubMed citation Europe PMC
8867920 PubMed citation Europe PMC
9430412 PubMed citation Europe PMC
Last Modified
04 June 2021