CHEBI:183368 - 7β-hydroxydehydroepiandrosterone

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name 7β-hydroxydehydroepiandrosterone
ChEBI ID CHEBI:183368
ChEBI ASCII Name 7beta-hydroxydehydroepiandrosterone
Definition An androstanoid that is dehydroepiandrosterone carrying an additional hydroxy substituent at the 7β-position. It is a metabolite of dehydroepiandrosterone.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter MetaboLights
Supplier Information
Download Molfile XML SDF
Wikipedia License
Waiting for wikipedia content
Read full article at Wikipedia
Formula C19H28O3
Net Charge 0
Average Mass 304.430
Monoisotopic Mass 304.20384
InChI InChI=1S/C19H28O3/c1-18-7-5-12(20)9-11(18)10-15(21)17-13-3-4-16(22)19(13,2)8-6-14(17)18/h10,12-15,17,20-21H,3-9H2,1-2H3/t12-,13-,14-,15-,17-,18-,19-/m0/s1
InChIKey OLPSAOWBSPXZEA-GCNMQWDSSA-N
SMILES [H][C@@]12CCC(=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])[C@@H](O)C=C2C[C@@H](O)CC[C@]12C
Metabolite of Species Details
Bombus terrestris (NCBI:txid30195) Found in hemolymph (BTO:0000572). See: MetaboLights Study
Bombus terrestris (NCBI:txid30195) Found in hindgut (BTO:0000510). See: MetaboLights Study
Bombus terrestris (NCBI:txid30195) Found in brain (BTO:0000142). See: MetaboLights Study
Homo sapiens (NCBI:txid9606) Found in blood serum (BTO:0000133). See: PubMed
Roles Classification
Biological Role(s): estrogen
A hormone that stimulates or controls the development and maintenance of female sex characteristics in mammals by binding to oestrogen receptors. The oestrogens are named for their importance in the oestrous cycle. The oestrogens that occur naturally in the body, notably estrone, estradiol, estriol, and estetrol are steroids. Other compounds with oestrogenic activity are produced by plants (phytoestrogens) and fungi (mycoestrogens); synthetic compounds with oestrogenic activity are known as xenoestrogens.
human blood serum metabolite
Any metabolite (endogenous or exogenous) found in human blood serum samples.
animal metabolite
Any eukaryotic metabolite produced during a metabolic reaction in animals that include diverse creatures from sponges, insects to mammals.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing 7β-hydroxydehydroepiandrosterone (CHEBI:183368) has functional parent dehydroepiandrosterone (CHEBI:28689)
7β-hydroxydehydroepiandrosterone (CHEBI:183368) has role animal metabolite (CHEBI:75767)
7β-hydroxydehydroepiandrosterone (CHEBI:183368) has role estrogen (CHEBI:50114)
7β-hydroxydehydroepiandrosterone (CHEBI:183368) has role human blood serum metabolite (CHEBI:85234)
7β-hydroxydehydroepiandrosterone (CHEBI:183368) is a 17-oxo steroid (CHEBI:19168)
7β-hydroxydehydroepiandrosterone (CHEBI:183368) is a 3β-hydroxy-Δ5-steroid (CHEBI:1722)
7β-hydroxydehydroepiandrosterone (CHEBI:183368) is a 7β-hydroxy steroid (CHEBI:35349)
7β-hydroxydehydroepiandrosterone (CHEBI:183368) is a androstanoid (CHEBI:50402)
IUPAC Name
3β,7β-dihydroxyandrost-5-en-17-one
Synonyms Sources
(3aS,3bR,4R,7S,9aR,9bS,11aS)-4,7-dihydroxy-9a,11a-dimethyl-2,3,3a,3b,4,6,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[a]phenanthren-1-one IUPAC
(3β,7β)-3,7-dihydroxyandrost-5-en-17-one ChemIDplus
3β,7β-dihydroxy-5-androsten-17-one ChEBI
3β,7β-dihydroxy-5-androstene-17-one ChEBI
3β,7β-dihydroxyandrost-5-en-17-one UniProt
7-β-OH-DHEA ChemIDplus
7β-hydroxy-DHEA ChemIDplus
androst-5-en-17-one-3β,7β-diol ChemIDplus
androst-5-ene-17-one-3β,7β-diol ChemIDplus
androst-5-ene-3β,7β-diol-17-one ChemIDplus
Manual Xrefs Databases
7%CE%B2-Hydroxy-DHEA Wikipedia
7993704 ChemSpider
FDB023384 FooDB
HMDB0004624 HMDB
LMST02020106 LIPID MAPS
View more database links
Registry Number Type Source
2487-48-1 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
10030693 PubMed citation Europe PMC
10659701 PubMed citation Europe PMC
14977864 PubMed citation Europe PMC
15698552 PubMed citation Europe PMC
15784286 PubMed citation Europe PMC
16238456 PubMed citation Europe PMC
16603347 PubMed citation Europe PMC
16713254 PubMed citation Europe PMC
16916745 PubMed citation Europe PMC
17078923 PubMed citation Europe PMC
17152345 PubMed citation Europe PMC
17467270 PubMed citation Europe PMC
18555503 PubMed citation Europe PMC
19167490 PubMed citation Europe PMC
26680473 PubMed citation Europe PMC
26680484 PubMed citation Europe PMC
Last Modified
18 May 2023