CHEBI:90879 - tipiracil

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ChEBI Name tipiracil
ChEBI ID CHEBI:90879
Definition A member of the class of pyrimidones that is uracil substituted by chloro and (2-iminopyrrolidin-1-yl)methyl groups at positions 5 and 6 respectively. Used (as the hydrochloride salt) in combination with trifluridine, a nucleoside metabolic inhibitor, for treatment of advanced/relapsed unresectable colorectal cancer.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Roles Classification
Biological Role(s): EC 2.4.2.4 (thymidine phosphorylase) inhibitor
An EC 2.4.2.* (pentosyltransferase) inhibitor that interferes with the action of thymidine phosphorylase (EC 2.4.2.4).
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
Related Structures
tipiracil is a Structural Derivative of
uracil
Mass : 112.08684
Formula : C4H4N2O2
17568
tipiracil is a Conjugate Base of
tipiracil(1+)
Mass : 243.670
Formula : C9H12ClN4O2
90880
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