CHEBI:90863 - sonidegib

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name sonidegib
ChEBI ID CHEBI:90863
Definition A member of the classo of biphenyls that is the amide obtained by formal condensation of the carboxy group of 2-methyl-4'-(trifluoromethoxy)[1,1'-biphenyl]-3-carboxylic acid with the amino group of 6-(2,6-dimethylmorpholin-4-yl)pyridin-3-amine. Used (as its phosphate salt) for treatment of locally advanced basal cell carcinoma.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): Hedgehog signaling pathway inhibitor
Any pathway inhibitor that inhibits the Hedgehog signalling pathway.
SMO receptor antagonist
An antagonist that interferes with the action of smoothened (SMO) receptor.
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
Related Structures
sonidegib is a Structural Derivative of
ammonia
Mass : 17.03056
Formula : H3N
16134
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