CHEBI:78030 - LGK974

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ChEBI Name LGK974
ChEBI ID CHEBI:78030
Definition A carboxamide, the structure of which is that of acetamide substituted on carbon by a 2',3-dimethyl-2,4'-bipyridin-5-yl group and on nitrogen by a 5-(pyrazin-2-yl)pyridin-2-yl group. It is a highly potent, selective and orally bioavailable Porcupine inhibitor (a Wnt signalling inhibitor).
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Roles Classification
Biological Role(s): Wnt signalling inhibitor
A substance that inhibits any of the Wnt signalling pathway, a group of signal transduction pathways made of proteins that pass signals from outside of a cell through cell surface receptors to the inside of the cell.
Related Structures
LGK974 is a Structural Derivative of
acetamide
Mass : 59.06724
Formula : C2H5NO
27856
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