CHEBI:76649 - astressin

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ChEBI Name astressin
ChEBI ID CHEBI:76649
Definition A 30-membered homodetic cyclic peptide comprising the sequence D-Phe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Nle-Ala-Arg-Ala-Glu-Gln-Leu-Ala-Gln-Glu-Ala-His-Lys-Asn-Arg-Lys-Leu-Nle-Glu-Ile-Ile-NH2 cyclised by an amide bridge, formed by condensation of the side-chain carboxy group of the Glu residue at position 19 and the side-chain amino group of the Lys residue at position 22.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Sandra Orchard
Supplier Information
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Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): corticotropin-releasing factor receptor antagonist
A hormone antagonist that blocks corticotropin-releasing factor receptors
Application(s): corticotropin-releasing factor receptor antagonist
A hormone antagonist that blocks corticotropin-releasing factor receptors
neuroprotective agent
Any compound that can be used for the treatment of neurodegenerative disorders.
Related Structures
astressin is a Structural Derivative of
ammonia
Mass : 17.03056
Formula : H3N
16134
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