CHEBI:66461 - semicochliodinol A

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ChEBI Name semicochliodinol A
ChEBI ID CHEBI:66461
Definition A bisindole alkaloid that is quinone bearing hydroxy substituents at positions 2 and 5 and two indol-3-yl groups at positions 3 and 6, one of which is carrying a prenyl group at position 5. Isolated from the culture broth of Chrysosporium merdarium, it acts as an inhibitor of HIV-1 protease and EGF-R protein tyrosine kinase.
Stars This entity has been manually annotated by the ChEBI Team.
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Roles Classification
Biological Role(s): metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
(via alkaloid )
HIV protease inhibitor
An inhibitor of HIV protease, an enzyme required for production of proteins needed for viral assembly.
epidermal growth factor receptor antagonist
An antagonist at the epidermal growth factor receptor.
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