CHEBI:65651 - colossolactone VIII

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ChEBI Name colossolactone VIII
ChEBI ID CHEBI:65651
Definition A tetracyclic triterpenoid that is A,B-dihomo-19-nor-4-oxalanosta-1,8,19,24-tetraen-26,22-olide substituted by an acetoxy group at position 15, a hydroxy group at position 23 and an oxo group at position 3 (the 22S, 23R stereoisomer). It is isolated from the fruiting bodies of the Vietnamese mushroom Ganoderma colossum and displays inhibitory activity towards the enzyme HIV protease.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Roles Classification
Biological Role(s): HIV protease inhibitor
An inhibitor of HIV protease, an enzyme required for production of proteins needed for viral assembly.
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
Related Structures
colossolactone VIII is a Structural Derivative of
lanostane
Mass : 414.74976
Formula : C30H54
20265 		acetic acid
Mass : 60.05200
Formula : C2H4O2
15366 		triterpene
Definition : A C30 terpene.
 terpene
Definition : A hydrocarbon of biological origin having carbon skeleton formally derived from isoprene [CH22C(CH3)CH2CH2].
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