CHEBI:4392 - demeclocycline

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ChEBI Name demeclocycline
ChEBI ID CHEBI:4392
Definition Tetracycline which lacks the methyl substituent at position 7 and in which the hydrogen para- to the phenolic hydroxy group is substituted by chlorine. Like tetracycline, it is an antibiotic, but being excreted more slowly, effective blood levels are maintained for longer. It is used (mainly as the hydrochloride) for the treatment of Lyme disease, acne and bronchitis, as well as for hyponatraemia (low blood sodium concentration) due to the syndrome of inappropriate antidiuretic hormone (SIADH) where fluid restriction alone has been ineffective.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:554084
Supplier Information
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Roles Classification
Biological Role(s): antibacterial drug
A drug used to treat or prevent bacterial infections.
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
(via tetracyclines )
Application(s): antibacterial drug
A drug used to treat or prevent bacterial infections.
aquaretic
A class of diuretics which promote aquaresis (the excretion of water without electrolyte loss).
geroprotector
Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.
Related Structures
demeclocycline is a Structural Derivative of
tetracene
Mass : 228.28788
Formula : C18H12
32600
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