CHEBI:2639 - amiloride

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ChEBI Name amiloride
ChEBI ID CHEBI:2639
Definition A member of the class of pyrazines resulting from the formal monoacylation of guanidine with the carboxy group of 3,5-diamino-6-chloropyrazine-2-carboxylic acid.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:47210
Supplier Information
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Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): sodium channel blocker
An agent that inhibits sodium influx through cell membranes.
Application(s): diuretic
An agent that promotes the excretion of urine through its effects on kidney function.
Related Structures
amiloride is a Functional Parent of
5-(N,N-hexamethylene)amiloride
Mass : 311.77100
Formula : C12H18ClN7O
76400 		5-(N-methyl-N-propyl)amiloride
Mass : 285.734
Formula : C10H16ClN7O
138016 		ethylisopropylamiloride
Mass : 299.760
Formula : C11H18ClN7O
136538
amiloride is a Structural Derivative of
ammonia
Mass : 17.03056
Formula : H3N
16134
amiloride is a Conjugate Base of
amiloride(1+)
Mass : 230.63400
Formula : C6H9ClN7O
84745
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