CHEBI:149519 - PFI-3

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ChEBI Name PFI-3
ChEBI ID CHEBI:149519
Definition An azabicycloalkane that is (1R,4R)-2,5-diazabicyclo[2.2.1]heptane which is substituted at position 2 by a 3-(2-hydroxyphenyl)-3-oxoprop-1-en-1-yl group and at position 5 by a pyridin-2-yl group. It is a potent and selective inhibitor of polybromo 1 (Kd = 48 nM), SMARCA2 and SMARCA4 (Kd = 89 nM) bromodomains.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Sabrina Toro
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