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CHEBI:8378 - prednisolone
| Formula | C21H28O5 |
| Net Charge | 0 |
| Average Mass | 360.450 |
| Monoisotopic Mass | 360.19367 |
| SMILES | [H][C@@]12CC[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)C=C[C@@]21C |
| InChI | InChI=1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-16,18,22,24,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1 |
| InChIKey | OIGNJSKKLXVSLS-VWUMJDOOSA-N |
| Wikipedia |
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| Roles Classification |
|---|
| Chemical Role: | environmental contaminant Any minor or unwanted substance introduced into the environment that can have undesired effects. |
| Biological Roles: | xenobiotic A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means. adrenergic agent Any agent that acts on an adrenergic receptor or affects the life cycle of an adrenergic transmitter. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. hormone Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds. |
| Applications: | adrenergic agent Any agent that acts on an adrenergic receptor or affects the life cycle of an adrenergic transmitter. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. anti-inflammatory drug A substance that reduces or suppresses inflammation. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| prednisolone (CHEBI:8378) has functional parent Δ1-progesterone (CHEBI:34073) |
| prednisolone (CHEBI:8378) has role adrenergic agent (CHEBI:37962) |
| prednisolone (CHEBI:8378) has role anti-inflammatory drug (CHEBI:35472) |
| prednisolone (CHEBI:8378) has role antineoplastic agent (CHEBI:35610) |
| prednisolone (CHEBI:8378) has role drug metabolite (CHEBI:49103) |
| prednisolone (CHEBI:8378) has role environmental contaminant (CHEBI:78298) |
| prednisolone (CHEBI:8378) has role immunosuppressive agent (CHEBI:35705) |
| prednisolone (CHEBI:8378) has role xenobiotic (CHEBI:35703) |
| prednisolone (CHEBI:8378) is a 11β-hydroxy steroid (CHEBI:35346) |
| prednisolone (CHEBI:8378) is a 17α-hydroxy steroid (CHEBI:35342) |
| prednisolone (CHEBI:8378) is a 20-oxo steroid (CHEBI:36885) |
| prednisolone (CHEBI:8378) is a 21-hydroxy steroid (CHEBI:35344) |
| prednisolone (CHEBI:8378) is a 3-oxo-Δ1,Δ4-steroid (CHEBI:77166) |
| prednisolone (CHEBI:8378) is a C21-steroid (CHEBI:61313) |
| prednisolone (CHEBI:8378) is a glucocorticoid (CHEBI:24261) |
| prednisolone (CHEBI:8378) is a primary α-hydroxy ketone (CHEBI:139590) |
| prednisolone (CHEBI:8378) is a tertiary α-hydroxy ketone (CHEBI:139592) |
| Incoming Relation(s) |
| 16-hydroxyprednisolone (CHEBI:196948) has functional parent prednisolone (CHEBI:8378) |
| 20α-dihydroprednisolone (CHEBI:166776) has functional parent prednisolone (CHEBI:8378) |
| 20β-dihydroprednisolone (CHEBI:180696) has functional parent prednisolone (CHEBI:8378) |
| 6-methylprednisolone (CHEBI:50366) has functional parent prednisolone (CHEBI:8378) |
| 6α-hydroxyprednisolone (CHEBI:180921) has functional parent prednisolone (CHEBI:8378) |
| 6β-hydroxyprednisolone (CHEBI:180697) has functional parent prednisolone (CHEBI:8378) |
| alclometasone (CHEBI:53776) has functional parent prednisolone (CHEBI:8378) |
| alclometasone dipropionate (CHEBI:31184) has functional parent prednisolone (CHEBI:8378) |
| beclomethasone (CHEBI:3001) has functional parent prednisolone (CHEBI:8378) |
| prednisolone phosphate (CHEBI:145705) has functional parent prednisolone (CHEBI:8378) |
| prednisolone succinate (CHEBI:135745) has functional parent prednisolone (CHEBI:8378) |
| prednisolone-16-carboxylic acid (CHEBI:47888) has functional parent prednisolone (CHEBI:8378) |
| Δ6-prednisolone (CHEBI:180920) has functional parent prednisolone (CHEBI:8378) |
| IUPAC Name |
|---|
| 11β,17,21-trihydroxypregna-1,4-diene-3,20-dione |
| INNs | Source |
|---|---|
| prednisolonum | ChemIDplus |
| prednisolona | ChemIDplus |
| prednisolone | WHO MedNet |
| prednisolone | ChemIDplus |
| Synonyms | Source |
|---|---|
| 1,4-pregnadiene-11β,17α,21-triol-3,20-dione | ChemIDplus |
| 1,4-pregnadiene-3,20-dione-11β,17α,21-triol | ChemIDplus |
| 3,20-dioxo-11β,17α,21-trihydroxy-1,4-pregnadiene | ChemIDplus |
| metacortandralone | ChemIDplus |
| Δ1-dehydrocortisol | ChemIDplus |
| Δ1-hydrocortisone | ChemIDplus |
| Manual Xrefs | Databases |
|---|---|
| C07369 | KEGG COMPOUND |
| Prednisolone | Wikipedia |
| DB00860 | DrugBank |
| D00472 | KEGG DRUG |
| HMDB0014998 | HMDB |
| 2245 | DrugCentral |
| 1848 | VSDB |
| Registry Numbers | Sources |
|---|---|
| Reaxys:1354103 | Reaxys |
| CAS:50-24-8 | KEGG COMPOUND |
| CAS:50-24-8 | ChemIDplus |
| Citations |
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