EMBL-EBI | Chemical Biology | ChEBI
Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search
CHEBI:15765 - L-dopa
| Formula | C9H11NO4 |
| Net Charge | 0 |
| Average Mass | 197.190 |
| Monoisotopic Mass | 197.06881 |
| SMILES | N[C@@H](Cc1ccc(O)c(O)c1)C(=O)O |
| InChI | InChI=1S/C9H11NO4/c10-6(9(13)14)3-5-1-2-7(11)8(12)4-5/h1-2,4,6,11-12H,3,10H2,(H,13,14)/t6-/m0/s1 |
| InChIKey | WTDRDQBEARUVNC-LURJTMIESA-N |
| Wikipedia |
|---|
| Species of Metabolite | Component | Source | Comments |
|---|---|---|---|
| Homo sapiens (ncbitaxon:9606) | - | DOI (10.1038/nbt.2488) | |
| Mus musculus (ncbitaxon:10090) | - | PubMed (19425150) | Source: BioModels - MODEL1507180067 |
| Roles Classification |
|---|
| Chemical Roles: | Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). Bronsted acid A molecular entity capable of donating a hydron to an acceptor (Brønsted base). Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). Bronsted acid A molecular entity capable of donating a hydron to an acceptor (Brønsted base). |
| Biological Roles: | hapten Any substance capable of eliciting an immune response only when attached to a large carrier such as a protein. Examples include dinitrophenols; oligosaccharides; peptides; and heavy metals. neurotoxin A poison that interferes with the functions of the nervous system. human metabolite Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens). mouse metabolite Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus). plant metabolite Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms. allelochemical A class of secondary metabolites developed by many plants to influence the behaviour, growth or survival of herbivores, and thus acting as a defence against herbivory. dopaminergic agent A drug used for its effects on dopamine receptors, on the life cycle of dopamine, or on the survival of dopaminergic neurons. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. human metabolite Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens). |
| Applications: | antidepressant Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. anti-asthmatic agent Any compound that has anti-asthmatic effects. neuroprotective agent Any compound that can be used for the treatment of neurodegenerative disorders. antiparkinson drug A drug used in the treatment of Parkinson's disease. prodrug A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug. dopaminergic agent A drug used for its effects on dopamine receptors, on the life cycle of dopamine, or on the survival of dopaminergic neurons. vasoconstrictor agent Drug used to cause constriction of the blood vessels. antipsychotic agent Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. antidyskinesia agent Any compound which can be used to treat or alleviate the symptoms of dyskinesia. ophthalmology drug Any compound used for the treatment of eye conditions or eye diseases. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| L-dopa (CHEBI:15765) has role allelochemical (CHEBI:62215) |
| L-dopa (CHEBI:15765) has role analgesic (CHEBI:35480) |
| L-dopa (CHEBI:15765) has role anti-asthmatic agent (CHEBI:65023) |
| L-dopa (CHEBI:15765) has role antidepressant (CHEBI:35469) |
| L-dopa (CHEBI:15765) has role antidyskinesia agent (CHEBI:66956) |
| L-dopa (CHEBI:15765) has role antiparkinson drug (CHEBI:48407) |
| L-dopa (CHEBI:15765) has role antipsychotic agent (CHEBI:35476) |
| L-dopa (CHEBI:15765) has role dopaminergic agent (CHEBI:48560) |
| L-dopa (CHEBI:15765) has role hapten (CHEBI:59174) |
| L-dopa (CHEBI:15765) has role human metabolite (CHEBI:77746) |
| L-dopa (CHEBI:15765) has role mouse metabolite (CHEBI:75771) |
| L-dopa (CHEBI:15765) has role neuroprotective agent (CHEBI:63726) |
| L-dopa (CHEBI:15765) has role neurotoxin (CHEBI:50910) |
| L-dopa (CHEBI:15765) has role ophthalmology drug (CHEBI:66981) |
| L-dopa (CHEBI:15765) has role plant growth retardant (CHEBI:35219) |
| L-dopa (CHEBI:15765) has role plant metabolite (CHEBI:76924) |
| L-dopa (CHEBI:15765) has role prodrug (CHEBI:50266) |
| L-dopa (CHEBI:15765) has role vasoconstrictor agent (CHEBI:50514) |
| L-dopa (CHEBI:15765) is a L-tyrosine derivative (CHEBI:27177) |
| L-dopa (CHEBI:15765) is a dopa (CHEBI:49168) |
| L-dopa (CHEBI:15765) is a non-proteinogenic L-α-amino acid (CHEBI:83822) |
| L-dopa (CHEBI:15765) is conjugate acid of L-dopa(1−) (CHEBI:67012) |
| L-dopa (CHEBI:15765) is enantiomer of D-dopa (CHEBI:49169) |
| L-dopa (CHEBI:15765) is tautomer of L-dopa zwitterion (CHEBI:57504) |
| Incoming Relation(s) |
| N-methyl-L-dopa (CHEBI:167646) has functional parent L-dopa (CHEBI:15765) |
| 2-S-cysteinyl-DOPA (CHEBI:84296) has functional parent L-dopa (CHEBI:15765) |
| 2,5-S,S'-dicysteinyldopa (CHEBI:84298) has functional parent L-dopa (CHEBI:15765) |
| 3-O-methyldopa (CHEBI:82913) has functional parent L-dopa (CHEBI:15765) |
| 3,4-dimethoxy-L-phenylalanine (CHEBI:229731) has functional parent L-dopa (CHEBI:15765) |
| 4-O-methyl-L-dopa (CHEBI:193023) has functional parent L-dopa (CHEBI:15765) |
| 6-fluoro-L-dopa (CHEBI:49163) has functional parent L-dopa (CHEBI:15765) |
| 6-hydroxy-L-dopa (CHEBI:72753) has functional parent L-dopa (CHEBI:15765) |
| foslevodopa (CHEBI:192509) has functional parent L-dopa (CHEBI:15765) |
| L-dopa(1−) (CHEBI:67012) is conjugate base of L-dopa (CHEBI:15765) |
| D-dopa (CHEBI:49169) is enantiomer of L-dopa (CHEBI:15765) |
| L-dopa zwitterion (CHEBI:57504) is tautomer of L-dopa (CHEBI:15765) |
| IUPAC Names |
|---|
| (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid |
| L-dopa |
| INNs | Source |
|---|---|
| levodopa | KEGG DRUG |
| levodopum | ChemIDplus |
| Synonyms | Source |
|---|---|
| (−)-3-(3,4-dihydroxyphenyl)-L-alanine | ChemIDplus |
| 3,4-Dihydroxy-L-phenylalanine | KEGG COMPOUND |
| 3,4-DIHYDROXYPHENYLALANINE | PDBeChem |
| 3-Hydroxy-L-tyrosine | KEGG COMPOUND |
| Cvt-301 | ChEMBL |
| Dihydroxy-L-phenylalanine | KEGG COMPOUND |
| Brand Names | Source |
|---|---|
| Brocadopa | ChEMBL |
| Dopar | KEGG DRUG |
| Inbrija | ChEMBL |
| Levodopa component of /carbidopa/entacapone orion | ChEMBL |
| Levodopa component of corbilta | ChEMBL |
| Levodopa component of crexont | ChEMBL |
| Citations |
|---|