Current Composition of Human UniProt-GOA

Current Composition of Human GOA



The following table describes the latest version of GOA Human (version 184), released on 10 October, 2018 and assembled using the publicly released data available in the source databases on 06 October, 2018.


GO Annotation Source Number of Associations Number of Distinct Gene Products
Total GOA annotations 619372 69722
Total Electronic GO annotation 199042 63301
Total Manual GO annotations 420330 25543
Manual GO annotation by UniProt (EBI Curators) 65403 10460
Manual GO annotation by UniProt (SIB Curators) 51285 7678
Manual GO annotation by UniProt (PIR Curators) 264 71
Total number of Pubmed references 283913
Number of distinct Pubmed references 37128
Electronic GO annotation using InterPro to GO mapping 63739 30658
Electronic GO annotation using Swiss-Prot keyword to GO mapping 29518 20777
Electronic GO annotation using UniProt Subcellular Location to GO mapping 8627 6844
Electronic GO annotation using EC to GO mapping 1597 1245
Electronic GO annotation using projections based on Ensembl orthologs 39135 6639
Electronic GO annotation using UniPathway to GO mapping 794 764
Electronic GO annotation using UniRule to GO mapping 2915 2078
Electronic GO annotation using RNAcentral Rfam to GO mapping 34814 15699
Logical inferences based on GOC rules and annotations from electronic sources 11162 8683
Manual GO annotation by Proteome Inc. extracted from Locus Link 8528 4159
Manual GO annotation by AgBase 1202 464
Manual GO annotation by MGI 4608 2007
Manual GO annotation by SGD 26 13
Manual GO annotation by FB 300 141
Manual GO annotation by BHF-UCL 31617 3642
Manual GO annotation by HGNC 2942 697
Manual GO annotation by WormBase 172 78
Manual GO annotation by Reactome 94452 9027
Manual GO annotation by IntAct 72702 9405
Manual GO annotation by GDB 52 32
Manual GO annotation by LIFEdb 453 450
Manual GO annotation by DictyBase 8 6
Manual GO annotation by Human Protein Atlas 16316 9104
Manual GO annotation by DFLAT 231 64
Manual GO annotation by MTBBASE 14 8
Manual GO annotation by RefGenome 50813 10880
Manual GO annotation by NTNU_SB 3852 1564
Manual GO annotation by CACAO 589 367
Manual GO annotation by UniProt for Automated Function Prediction SIG 2549 545
Manual GO annotation by ParkinsonsUK-UCL 4581 828
Manual GO annotation by SYSCILIA_CCNET 162 41
Manual GO annotation by Alzheimers Project at University of Toronto 193 17
Manual GO annotation by GO_Central 520 195
Manual GO annotation by SynGO 10 8
Manual GO annotation by SynGO (UCL Curators) 33 11
Manual GO annotation by ARUK-UCL 3407 414
Manual GO annotation by Complex Portal 2357 351
Manual GO annotation by YuBioLab 152 145
Manual GO annotation by SynGO (via Noctua) 537 92
Logical inferences based on GOC rules and annotations from manual sources 6741 4207
Logical inferences based on GOC rules and annotations from manual and electronic sources 17903 11268