Current Composition of Human UniProt-GOA

Current Composition of Human GOA



The following table describes the latest version of GOA Human (version 186), released on 05 December, 2018 and assembled using the publicly released data available in the source databases on 01 December, 2018.


GO Annotation Source Number of Associations Number of Distinct Gene Products
Total GOA annotations 624984 70443
Total Electronic GO annotation 200636 63984
Total Manual GO annotations 424348 25631
Manual GO annotation by UniProt (EBI Curators) 65632 10490
Manual GO annotation by UniProt (SIB Curators) 52567 7806
Manual GO annotation by UniProt (PIR Curators) 285 76
Total number of Pubmed references 287719
Number of distinct Pubmed references 37508
Electronic GO annotation using InterPro to GO mapping 65216 31336
Electronic GO annotation using Swiss-Prot keyword to GO mapping 29525 20761
Electronic GO annotation using UniProt Subcellular Location to GO mapping 8649 6854
Electronic GO annotation using EC to GO mapping 1555 1231
Electronic GO annotation using projections based on Ensembl orthologs 38995 6628
Electronic GO annotation using UniPathway to GO mapping 794 765
Electronic GO annotation using UniRule to GO mapping 3010 2126
Electronic GO annotation using RNAcentral Rfam to GO mapping 34814 15699
Logical inferences based on GOC rules and annotations from electronic sources 11326 8818
Manual GO annotation by Proteome Inc. extracted from Locus Link 8391 4114
Manual GO annotation by AgBase 1202 464
Manual GO annotation by MGI 4610 2009
Manual GO annotation by SGD 26 13
Manual GO annotation by FB 300 141
Manual GO annotation by BHF-UCL 31624 3643
Manual GO annotation by HGNC 2945 698
Manual GO annotation by WormBase 172 78
Manual GO annotation by Reactome 94452 9027
Manual GO annotation by IntAct 73234 9450
Manual GO annotation by GDB 53 32
Manual GO annotation by LIFEdb 453 450
Manual GO annotation by DictyBase 8 6
Manual GO annotation by Human Protein Atlas 16308 9099
Manual GO annotation by DFLAT 231 64
Manual GO annotation by MTBBASE 14 8
Manual GO annotation by RefGenome 52136 11077
Manual GO annotation by NTNU_SB 3848 1564
Manual GO annotation by CACAO 589 367
Manual GO annotation by UniProt for Automated Function Prediction SIG 2545 545
Manual GO annotation by ParkinsonsUK-UCL 4578 828
Manual GO annotation by SYSCILIA_CCNET 162 41
Manual GO annotation by Alzheimers Project at University of Toronto 193 17
Manual GO annotation by GO_Central 520 195
Manual GO annotation by SynGO 10 8
Manual GO annotation by SynGO (UCL Curators) 33 11
Manual GO annotation by ARUK-UCL 4148 541
Manual GO annotation by Complex Portal 2390 357
Manual GO annotation by YuBioLab 152 145
Manual GO annotation by SynGO (via Noctua) 537 92
Logical inferences based on GOC rules and annotations from manual sources 6752 4199
Logical inferences based on GOC rules and annotations from manual and electronic sources 18078 11386