Current Composition of Human UniProt-GOA

Current Composition of Human GOA



The following table describes the latest version of GOA Human (version 174), released on 22 November, 2017 and assembled using the publicly released data available in the source databases on 18 November, 2017.


GO Annotation Source Number of Associations Number of Distinct Gene Products
Total GOA annotations 544276 51544
Total Electronic GO annotation 162143 45662
Total Manual GO annotations 382133 24341
Manual GO annotation by UniProt (EBI Curators) 66276 10569
Manual GO annotation by UniProt (SIB Curators) 46785 7217
Manual GO annotation by UniProt (PIR Curators) 231 63
Total number of Pubmed references 224125
Number of distinct Pubmed references 35783
Electronic GO annotation using InterPro to GO mapping 60591 28814
Electronic GO annotation using Swiss-Prot keyword to GO mapping 31406 20839
Electronic GO annotation using UniProt Subcellular Location to GO mapping 8983 7139
Electronic GO annotation using EC to GO mapping 1596 1229
Electronic GO annotation using projections based on Ensembl orthologs 39630 6752
Electronic GO annotation using UniPathway to GO mapping 794 762
Electronic GO annotation using UniRule to GO mapping 2659 1883
Logical inferences based on GOC rules and annotations from electronic sources 10425 7492
Manual GO annotation by Proteome Inc. extracted from Locus Link 9817 4410
Manual GO annotation by AgBase 1209 469
Manual GO annotation by MGI 4537 1974
Manual GO annotation by SGD 25 12
Manual GO annotation by FB 262 117
Manual GO annotation by BHF-UCL 29596 3523
Manual GO annotation by HGNC 2954 695
Manual GO annotation by WormBase 156 72
Manual GO annotation by Roslin Institute 1 1
Manual GO annotation by Reactome 96303 8959
Manual GO annotation by IntAct 72395 9410
Manual GO annotation by GDB 29 18
Manual GO annotation by LIFEdb 453 450
Manual GO annotation by DictyBase 8 6
Manual GO annotation by Human Protein Atlas 15274 8545
Manual GO annotation by DFLAT 232 64
Manual GO annotation by MTBBASE 14 8
Manual GO annotation by RefGenome 24235 7021
Manual GO annotation by NTNU_SB 951 299
Manual GO annotation by CACAO 592 369
Manual GO annotation by UniProt for Automated Function Prediction SIG 2532 543
Manual GO annotation by ParkinsonsUK-UCL 4661 878
Manual GO annotation by SYSCILIA_CCNET 162 41
Manual GO annotation by Alzheimers Project at University of Toronto 194 17
Manual GO annotation by GO_Central 451 166
Manual GO annotation by SynGO 10 8
Manual GO annotation by SynGO (UCL Curators) 25 8
Manual GO annotation by ARUK-UCL 1763 194
Logical inferences based on GOC rules and annotations from manual sources 6059 3881
Logical inferences based on GOC rules and annotations from manual and electronic sources 16484 9639
UniProt-GOA collaborates with

Cardiovascular Gene Ontology Annotation Initiative DictyBase Ensembl Compara Enzyme Nomenclature FlyBase  GO Consortium logo GUDMAP Gramene HAMAP HGNC HPA IntAct InterPro LIFEdb MGI MTBbase logo Reactome RI RGD SGD SwissProt TAIR TIGR WormBase ZFIN The Evidence & Conclusion Ontology