Current Composition of Human UniProt-GOA

Current Composition of Human GOA



The following table describes the latest version of GOA Human (version 180), released on 24 May, 2018 and assembled using the publicly released data available in the source databases on 19 May, 2018.


GO Annotation Source Number of Associations Number of Distinct Gene Products
Total GOA annotations 591994 67822
Total Electronic GO annotation 198226 61628
Total Manual GO annotations 393768 25206
Manual GO annotation by UniProt (EBI Curators) 64948 10396
Manual GO annotation by UniProt (SIB Curators) 48999 7463
Manual GO annotation by UniProt (PIR Curators) 257 70
Total number of Pubmed references 235361
Number of distinct Pubmed references 37136
Electronic GO annotation using InterPro to GO mapping 60849 28945
Electronic GO annotation using Swiss-Prot keyword to GO mapping 31503 21124
Electronic GO annotation using UniProt Subcellular Location to GO mapping 8935 7064
Electronic GO annotation using EC to GO mapping 1564 1236
Electronic GO annotation using projections based on Ensembl orthologs 38775 6603
Electronic GO annotation using UniPathway to GO mapping 812 780
Electronic GO annotation using UniRule to GO mapping 2855 2022
Electronic GO annotation using RNAcentral Rfam to GO mapping 34842 15713
Logical inferences based on GOC rules and annotations from electronic sources 11400 8792
Manual GO annotation by Proteome Inc. extracted from Locus Link 9277 4317
Manual GO annotation by AgBase 1205 468
Manual GO annotation by MGI 4578 1987
Manual GO annotation by SGD 26 13
Manual GO annotation by FB 300 141
Manual GO annotation by BHF-UCL 30668 3557
Manual GO annotation by HGNC 2952 697
Manual GO annotation by WormBase 171 78
Manual GO annotation by Reactome 93662 9016
Manual GO annotation by IntAct 78594 9569
Manual GO annotation by GDB 28 18
Manual GO annotation by LIFEdb 453 450
Manual GO annotation by DictyBase 8 6
Manual GO annotation by Human Protein Atlas 16328 9112
Manual GO annotation by DFLAT 231 64
Manual GO annotation by MTBBASE 14 8
Manual GO annotation by RefGenome 23973 7009
Manual GO annotation by NTNU_SB 3852 1564
Manual GO annotation by CACAO 589 367
Manual GO annotation by UniProt for Automated Function Prediction SIG 2552 545
Manual GO annotation by ParkinsonsUK-UCL 4590 829
Manual GO annotation by SYSCILIA_CCNET 162 41
Manual GO annotation by Alzheimers Project at University of Toronto 194 17
Manual GO annotation by GO_Central 518 193
Manual GO annotation by SynGO 10 8
Manual GO annotation by SynGO (UCL Curators) 33 11
Manual GO annotation by ARUK-UCL 2729 330
Manual GO annotation by Complex Portal 1867 319
Logical inferences based on GOC rules and annotations from manual sources 6691 4441
Logical inferences based on GOC rules and annotations from manual and electronic sources 18091 11545
UniProt-GOA collaborates with

Cardiovascular Gene Ontology Annotation Initiative DictyBase Ensembl Compara Enzyme Nomenclature FlyBase  GO Consortium logo GUDMAP Gramene HAMAP HGNC HPA IntAct InterPro LIFEdb MGI MTBbase logo Reactome RI RGD SGD SwissProt TAIR TIGR WormBase ZFIN The Evidence & Conclusion Ontology