Current Composition of Human UniProt-GOA

Current Composition of Human GOA



The following table describes the latest version of GOA Human (version 189), released on 10 April, 2019 and assembled using the publicly released data available in the source databases on 06 April, 2019.


GO Annotation Source Number of Associations Number of Distinct Gene Products
Total GOA annotations 631853 72182
Total Electronic GO annotation 204304 65622
Total Manual GO annotations 427549 25744
Manual GO annotation by UniProt (EBI Curators) 65612 10521
Manual GO annotation by UniProt (SIB Curators) 54690 7999
Manual GO annotation by UniProt (PIR Curators) 285 76
Total number of Pubmed references 290107
Number of distinct Pubmed references 37795
Electronic GO annotation using InterPro to GO mapping 64870 31296
Electronic GO annotation using Swiss-Prot keyword to GO mapping 29869 21033
Electronic GO annotation using UniProt Subcellular Location to GO mapping 8644 6859
Electronic GO annotation using EC to GO mapping 1766 1385
Electronic GO annotation using projections based on Ensembl orthologs 40093 6735
Electronic GO annotation using UniPathway to GO mapping 824 793
Electronic GO annotation using UniRule to GO mapping 3084 2157
Electronic GO annotation using RNAcentral Rfam to GO mapping 37723 17304
Logical inferences based on GOC rules and annotations from electronic sources 11420 8855
Manual GO annotation by Proteome Inc. extracted from Locus Link 8039 4017
Manual GO annotation by AgBase 1202 464
Manual GO annotation by MGI 4671 2034
Manual GO annotation by SGD 26 13
Manual GO annotation by FB 304 145
Manual GO annotation by BHF-UCL 32037 3667
Manual GO annotation by HGNC 2948 700
Manual GO annotation by WormBase 172 78
Manual GO annotation by Reactome 93711 9058
Manual GO annotation by IntAct 74249 9537
Manual GO annotation by GDB 52 32
Manual GO annotation by LIFEdb 453 450
Manual GO annotation by DictyBase 8 6
Manual GO annotation by Human Protein Atlas 16295 9093
Manual GO annotation by DFLAT 229 64
Manual GO annotation by MTBBASE 14 8
Manual GO annotation by RefGenome 51705 11242
Manual GO annotation by NTNU_SB 3834 1551
Manual GO annotation by CACAO 589 367
Manual GO annotation by UniProt for Automated Function Prediction SIG 2539 545
Manual GO annotation by ParkinsonsUK-UCL 4578 828
Manual GO annotation by SYSCILIA_CCNET 162 41
Manual GO annotation by Alzheimers Project at University of Toronto 191 17
Manual GO annotation by GO_Central 587 252
Manual GO annotation by SynGO 10 8
Manual GO annotation by SynGO (UCL Curators) 33 11
Manual GO annotation by ARUK-UCL 5155 695
Manual GO annotation by Complex Portal 2501 375
Manual GO annotation by YuBioLab 152 145
Manual GO annotation by SynGO (via Noctua) 516 91
Logical inferences based on GOC rules and annotations from manual sources 6011 3973
Logical inferences based on GOC rules and annotations from manual and electronic sources 17431 11259