Current Composition of Human UniProt-GOA

Current Composition of Human GOA



The following table describes the latest version of GOA Human (version 179), released on 25 April, 2018 and assembled using the publicly released data available in the source databases on 21 April, 2018.


GO Annotation Source Number of Associations Number of Distinct Gene Products
Total GOA annotations 548329 52033
Total Electronic GO annotation 161979 45879
Total Manual GO annotations 386350 25129
Manual GO annotation by UniProt (EBI Curators) 64904 10386
Manual GO annotation by UniProt (SIB Curators) 48463 7393
Manual GO annotation by UniProt (PIR Curators) 252 69
Total number of Pubmed references 228114
Number of distinct Pubmed references 36509
Electronic GO annotation using InterPro to GO mapping 60894 28942
Electronic GO annotation using Swiss-Prot keyword to GO mapping 31425 21069
Electronic GO annotation using UniProt Subcellular Location to GO mapping 8915 7046
Electronic GO annotation using EC to GO mapping 1548 1220
Electronic GO annotation using projections based on Ensembl orthologs 38782 6599
Electronic GO annotation using UniPathway to GO mapping 813 781
Electronic GO annotation using UniRule to GO mapping 2892 2035
Logical inferences based on GOC rules and annotations from electronic sources 10071 7467
Manual GO annotation by Proteome Inc. extracted from Locus Link 9444 4345
Manual GO annotation by AgBase 1208 468
Manual GO annotation by MGI 4562 1983
Manual GO annotation by SGD 26 13
Manual GO annotation by FB 298 140
Manual GO annotation by BHF-UCL 30396 3548
Manual GO annotation by HGNC 2953 697
Manual GO annotation by WormBase 172 78
Manual GO annotation by Reactome 93662 9016
Manual GO annotation by IntAct 71760 9300
Manual GO annotation by GDB 29 19
Manual GO annotation by LIFEdb 453 450
Manual GO annotation by DictyBase 8 6
Manual GO annotation by Human Protein Atlas 16328 9112
Manual GO annotation by DFLAT 231 64
Manual GO annotation by MTBBASE 14 8
Manual GO annotation by RefGenome 24019 7014
Manual GO annotation by NTNU_SB 3852 1564
Manual GO annotation by CACAO 590 367
Manual GO annotation by UniProt for Automated Function Prediction SIG 2557 545
Manual GO annotation by ParkinsonsUK-UCL 4588 829
Manual GO annotation by SYSCILIA_CCNET 162 41
Manual GO annotation by Alzheimers Project at University of Toronto 194 17
Manual GO annotation by GO_Central 518 193
Manual GO annotation by SynGO 10 8
Manual GO annotation by SynGO (UCL Curators) 33 11
Manual GO annotation by ARUK-UCL 2502 306
Manual GO annotation by Complex Portal 2162 326
Logical inferences based on GOC rules and annotations from manual sources 6639 4411
Logical inferences based on GOC rules and annotations from manual and electronic sources 16710 10194
UniProt-GOA collaborates with

Cardiovascular Gene Ontology Annotation Initiative DictyBase Ensembl Compara Enzyme Nomenclature FlyBase  GO Consortium logo GUDMAP Gramene HAMAP HGNC HPA IntAct InterPro LIFEdb MGI MTBbase logo Reactome RI RGD SGD SwissProt TAIR TIGR WormBase ZFIN The Evidence & Conclusion Ontology