Current Composition of Human UniProt-GOA

Current Composition of Human GOA



The following table describes the latest version of GOA Human (version 187), released on 16 January, 2019 and assembled using the publicly released data available in the source databases on 12 January, 2019.


GO Annotation Source Number of Associations Number of Distinct Gene Products
Total GOA annotations 627642 70544
Total Electronic GO annotation 202429 64014
Total Manual GO annotations 427093 25680
Manual GO annotation by UniProt (EBI Curators) 65430 10494
Manual GO annotation by UniProt (SIB Curators) 53158 7861
Manual GO annotation by UniProt (PIR Curators) 285 76
Total number of Pubmed references 290160
Number of distinct Pubmed references 37500
Electronic GO annotation using InterPro to GO mapping 64995 31348
Electronic GO annotation using Swiss-Prot keyword to GO mapping 29765 20969
Electronic GO annotation using UniProt Subcellular Location to GO mapping 8689 6892
Electronic GO annotation using EC to GO mapping 1742 1375
Electronic GO annotation using projections based on Ensembl orthologs 39251 6644
Electronic GO annotation using UniPathway to GO mapping 798 769
Electronic GO annotation using UniRule to GO mapping 3117 2162
Electronic GO annotation using RNAcentral Rfam to GO mapping 34814 15699
Logical inferences based on GOC rules and annotations from electronic sources 11364 8827
Manual GO annotation by Proteome Inc. extracted from Locus Link 8372 4103
Manual GO annotation by AgBase 1202 464
Manual GO annotation by MGI 4611 2010
Manual GO annotation by SGD 26 13
Manual GO annotation by FB 300 141
Manual GO annotation by BHF-UCL 33386 3663
Manual GO annotation by HGNC 2946 699
Manual GO annotation by WormBase 172 78
Manual GO annotation by Reactome 93712 9058
Manual GO annotation by IntAct 73841 9501
Manual GO annotation by GDB 52 32
Manual GO annotation by LIFEdb 453 450
Manual GO annotation by DictyBase 8 6
Manual GO annotation by Human Protein Atlas 16305 9097
Manual GO annotation by DFLAT 229 64
Manual GO annotation by MTBBASE 14 8
Manual GO annotation by RefGenome 52415 11224
Manual GO annotation by NTNU_SB 3848 1564
Manual GO annotation by CACAO 589 367
Manual GO annotation by UniProt for Automated Function Prediction SIG 2539 545
Manual GO annotation by ParkinsonsUK-UCL 4578 828
Manual GO annotation by SYSCILIA_CCNET 162 41
Manual GO annotation by Alzheimers Project at University of Toronto 191 17
Manual GO annotation by GO_Central 531 205
Manual GO annotation by SynGO 10 8
Manual GO annotation by SynGO (UCL Curators) 33 11
Manual GO annotation by ARUK-UCL 4551 594
Manual GO annotation by Complex Portal 2455 371
Manual GO annotation by YuBioLab 152 145
Manual GO annotation by SynGO (via Noctua) 537 92
Logical inferences based on GOC rules and annotations from manual sources 6014 3987
Logical inferences based on GOC rules and annotations from manual and electronic sources 17378 11239