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Cryo-EM structure of the SARS-CoV-2 S-6P in complex with 35B5 Fab(1 down RBD, state1)
Resolution: 3.69 Å
EM Method: Single-particle
Fitted PDBs: 7e9n
Q-score: 0.31
Wang X, Hu A, Chen X, Zhang Y, Yu F, Yue S, Li A, Zhang J, Pan Z, Yang Y, Lin Y, Gao L, Zhou J, Zhao J, Li F, Shi Y, Huang F, Yang X, Peng Y, Tu L, Zhang H, Zheng H, He J, Zhang H, Xu L, Huang Q, Zhu Y, Deng K, Ye L
Signal Transduct Target Ther (2022) 7 pp. 114- [ DOI: doi:10.1038/s41392-022-00954-8 ]
- Spike glycoprotein (124 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Complex of the sars-cov-2 s-6p with 35b5 fab(1 down rbd, state1) (Complex from Severe acute respiratory syndrome coronavirus 2)
- Heavy chain of 35b5 fab (25 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Light chain of 35b5 fab (23 kDa, Protein from Homo sapiens)
Cryo-EM structure of the SARS-CoV-2 S-6P in complex with Fab30
Resolution: 2.76 Å
EM Method: Single-particle
Fitted PDBs: 7enf
Q-score: 0.485
Wang X, Hu A, Chen X, Zhang Y, Yu F, Yue S, Li A, Zhang J, Pan Z, Yang Y, Lin Y, Gao L, Zhou J, Zhao J, Li F, Shi Y, Huang F, Yang X, Peng Y, Tu L, Zhang H, Zheng H, He J, Zhang H, Xu L, Huang Q, Zhu Y, Deng K, Ye L
Signal Transduct Target Ther (2022) 7 pp. 114- [ DOI: doi:10.1038/s41392-022-00954-8 ]
- Sars-cov-2 spike glycoprotein (Complex from Homo sapiens)
- Light chain of fab30 (24 kDa, Protein from Homo sapiens)
- Fab30 (Complex)
- Heavy chain of fab30 (24 kDa, Protein from Homo sapiens)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Complex of sars-cov-2 spike glycoprotein and fab30 (Complex from Severe acute respiratory syndrome coronavirus 2)
Resolution: 3.59 Å
EM Method: Single-particle
Fitted PDBs: 7eng
Q-score: 0.455
Wang X, Hu A, Chen X, Zhang Y, Yu F, Yue S, Li A, Zhang J, Pan Z, Yang Y, Lin Y, Gao L, Zhou J, Zhao J, Li F, Shi Y, Huang F, Yang X, Peng Y, Tu L, Zhang H, Zheng H, He J, Zhang H, Xu L, Huang Q, Zhu Y, Deng K, Ye L
Signal Transduct Target Ther (2022) 7 pp. 114- [ DOI: doi:10.1038/s41392-022-00954-8 ]
- Sars-cov-2 spike glycoprotein (Complex from Homo sapiens)
- Light chain of fab30 (24 kDa, Protein from Homo sapiens)
- Fab30 (Complex)
- Heavy chain of fab30 (24 kDa, Protein from Homo sapiens)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Complex of sars-cov-2 spike glycoprotein and fab30 (Complex from Severe acute respiratory syndrome coronavirus 2)
Resolution: 3.69 Å
EM Method: Single-particle
Fitted PDBs: 7e9p
Q-score: 0.463
Wang X, Hu A, Chen X, Zhang Y, Yu F, Yue S, Li A, Zhang J, Pan Z, Yang Y, Lin Y, Gao L, Zhou J, Zhao J, Li F, Shi Y, Huang F, Yang X, Peng Y, Tu L, Zhang H, Zheng H, He J, Zhang H, Xu L, Huang Q, Zhu Y, Deng K, Ye L
Signal Transduct Target Ther (2022) 7 pp. 114- [ DOI: doi:10.1038/s41392-022-00954-8 ]
- Sars-cov-2 spike glycoprotein (Complex from Homo sapiens)
- Complex of sars-cov-2 spike glycoprotein and 35b5 fab (state2) (Complex from Severe acute respiratory syndrome coronavirus 2)
- 35b5 fab (Complex)
- Light chain of 35b5 fab (23 kDa, Protein from Homo sapiens)
- Heavy chain of 35b5 fab (25 kDa, Protein from Homo sapiens)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Wang X, Hu A, Chen X, Zhang Y, Yu F, Yue S, Li A, Zhang J, Pan Z, Yang Y, Lin Y, Gao L, Zhou J, Zhao J, Li F, Shi Y, Huang F, Yang X, Peng Y, Tu L, Zhang H, Zheng H, He J, Zhang H, Xu L, Huang Q, Zhu Y, Deng K, Ye L
Signal Transduct Target Ther (2022) 7 pp. 114- [ DOI: doi:10.1038/s41392-022-00954-8 ]
- Sars-cov-2 spike glycoprotein (Complex from Homo sapiens)
- Complex of sars-cov-2 spike glycoprotein and 35b5 fab (state1) (Complex from Severe acute respiratory syndrome coronavirus 2)
- 35b5 fab (Complex)
- Heavy chain of 35b5 fab (25 kDa, Protein from Homo sapiens)
- Light chain of 35b5 fab (23 kDa, Protein from Homo sapiens)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure of the SARS-CoV-2 S-6P in complex with 35B5 Fab(3 up RBDs, state2)
Resolution: 3.41 Å
EM Method: Single-particle
Fitted PDBs: 7e9o
Q-score: 0.381
Wang X, Hu A, Chen X, Zhang Y, Yu F, Yue S, Li A, Zhang J, Pan Z, Yang Y, Lin Y, Gao L, Zhou J, Zhao J, Li F, Shi Y, Huang F, Yang X, Peng Y, Tu L, Zhang H, Zheng H, He J, Zhang H, Xu L, Huang Q, Zhu Y, Deng K, Ye L
Signal Transduct Target Ther (2022) 7 pp. 114- [ DOI: doi:10.1038/s41392-022-00954-8 ]
- Sars-cov-2 spike glycoprotein (Complex from Homo sapiens)
- Complex of sars-cov-2 spike glycoprotein and 35b5 fab (state2) (Complex from Severe acute respiratory syndrome coronavirus 2)
- 35b5 fab (Complex)
- Light chain of 35b5 fab (23 kDa, Protein from Homo sapiens)
- Heavy chain of 35b5 fab (25 kDa, Protein from Homo sapiens)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure of the SARS-CoV-2 S-6P in complex with 35B5 Fab(1 out RBD, state3)
Resolution: 3.65 Å
EM Method: Single-particle
Fitted PDBs: 7e9q
Q-score: 0.36
Wang X, Hu A, Chen X, Zhang Y, Yu F, Yue S, Li A, Zhang J, Pan Z, Yang Y, Lin Y, Gao L, Zhou J, Zhao J, Li F, Shi Y, Huang F, Yang X, Peng Y, Tu L, Zhang H, Zheng H, He J, Zhang H, Xu L, Huang Q, Zhu Y, Deng K, Ye L
Signal Transduct Target Ther (2022) 7 pp. 114- [ DOI: doi:10.1038/s41392-022-00954-8 ]
- Sars-cov-2 spike glycoprotein (Complex from Homo sapiens)
- 35b5 fab (Complex)
- Complex of sars-cov-2 spike glycoprotein and 35b5 fab (Complex from Severe acute respiratory syndrome coronavirus 2)
- Light chain of 35b5 fab (23 kDa, Protein from Homo sapiens)
- Heavy chain of 35b5 fab (25 kDa, Protein from Homo sapiens)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)