Round 52
This round is Closed
Announcement
We are announcing CAPRI Round 52, offering target T186, representing a large protein complex determined at high resolution by cryo-EM, by Prof. Rouslan Efremov, at the VIB-VUB center for structural biology, Brussels Belgium
The target is part of a stable sub-complex (peripheral arm) of the E.coli respiratory complex: NADH:Ubiquinone oxidoreductase, which comprised 6 polypeptides. One of the subunits has a ~100 residue loop, bound to a large pocket of the complex. The bound loop adopts a well-defined conformation that contains little secondary structure.
An adequate template representing a related complex from T.thermophilus, lacking the 100 residue loop of the E.coli complex is available. The main challenge of this target will be to correctly model the bound conformation of the ~100 residue loop in the E.coli complex.
Targets
Dates
Registration starts: May 6, 2021, midnight
| Target | Status | Prediction | Scoring | |||
|---|---|---|---|---|---|---|
| Start | End (server) | End (human) | Start | End | ||
| Target 186 | Closed | June 1, 2021, midnight | June 8, 2021, midnight | June 29, 2021, midnight | July 2, 2021, midnight | July 8, 2021, midnight |