Round 48

This round is Closed

Registration is closed Participant list


We are happy to announce CAPRI Round 48, with Targets 161 and 162.

Predictors and scorers are requested to register for the entire Round.

The system of both targets is a toxin-antitoxin complex of E.coli. This hetero-complex consists of a homo-dimer of the toxin protein, bound to 2 antitoxin molecules.

In this interesting system, the toxin homodimer in complex with the antitoxin (the bound form) forms a completely different dimer than the toxin homodimer in the unbound from.

The challenge for T161 will be to predict the bound form of the toxin homodimer.

The challenge for T162 will be to predict the structure of the full toxin-antitoxin complex.


Additional notes:

In Round 48 and following Rounds, we plan to rank prediction performance on the basis of the top 5 submitted models, and not the top 10 models, as done previously. 
Based on the recent assessments performed in CAPRI and in the CASP13-CAPRI  challenge,  it appeared that using the top 5 models to rank the prediction performance is quite adequate. So we will continue to do so.
Please note however, that we, the assessors,  will nevertheless continue to analyze how the performance varies when considering the top1 and top10 models, to try to monitor trends in model rankings by predictors.



Registration starts: Dec. 4, 2019

Target Status Prediction Scoring
Start End (server) End (human) Start End
Target 161 Closed Dec. 11, 2019 Dec. 16, 2019 Jan. 23, 2020 Jan. 27, 2020 Jan. 31, 2020
Target 162 Closed Feb. 3, 2020 Feb. 12, 2020 March 6, 2020 March 11, 2020 March 17, 2020