Structure for K777 (C01.075 inhibitor)

Summary Structure Literature

 

PDB Organism Resolution Comment
2P7U_A Trypanosoma brucei 1.65 Å complex with the vinyl sulfone derived inhibitor K11777
Catalytic residues are shown in ball-and-stick representation: Gln144 in light pink, Cys150 in yellow, His287 in purple and Asn307 in dark pink. The bound to inhibitor k777 is shown in grey ball-and-stick representation.
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TERTIARY STRUCTURE DATA
Comment Resolution PDB PDBe SCOP CATH PDBSum Proteopedia Reference
rhodesain ( Trypanosoma brucei)
complex with the vinyl sulfone derived inhibitor K11777 1.65 Å 2P7U 2P7U 2P7U 2P7U 2P7U 2P7U Kerr et al., 2009
cruzipain ( Trypanosoma cruzi)
complex with the vinyl sulfone derived inhibitor K11777 1.95 Å 2OZ2 2OZ2 2OZ2 2OZ2 2OZ2 2OZ2 Kerr et al., 2009