Structure for rupintrivir (C03.007 inhibitor)
| PDB | Organism | Resolution | Comment |
|---|---|---|---|
| 1CQQ_A | human rhinovirus 2 | 1.85 Å | complex with AG7088 inhibitor |
| Catalytic residues are shown in ball-and-stick representation: His1547 in purple, Glu1578 in pink and Cys1654 in yellow. | |||
 |
|||
| Show surface | |||
 |
|||
| TERTIARY STRUCTURE DATA | ||||||||
|---|---|---|---|---|---|---|---|---|
| Comment | Resolution | PDB | PDBe | SCOP | CATH | PDBSum | Proteopedia | Reference |
| subfamily C3A unassigned peptidases ( human coxsackievirus A16) | ||||||||
| complex with rupintrivir (ag7088) | 1.80 Å | 3SJI | 3SJI | 3SJI | 3SJI | 3SJI | 3SJI | |
| human enterovirus 71 3C peptidase ( human enterovirus 71) | ||||||||
| Glu71Asp mutant; complex with rupintrivir | 1.70 Å | 3QZQ | 3QZQ | 3QZQ | 3QZQ | 3QZQ | 3QZQ | |
| Glu71Ala mutant; complex with rupintrivir | 1.04 Å | 3QZR | 3QZR | 3QZR | 3QZR | 3QZR | 3QZR | |
| His133Gly mutant; complex with rupintrivir | 1.31 Å | 3R0F | 3R0F | 3R0F | 3R0F | 3R0F | 3R0F | |
| poliovirus capsid VP0-type self-cleaving protein ( human enterovirus 71) | ||||||||
| complex with rupintrivir (ag7088) | 1.70 Å | 3SJO | 3SJO | 3SJO | 3SJO | 3SJO | 3SJO | |
| human enterovirus 71 3C peptidase ( human enterovirus 71) | ||||||||
| complex with rupintrivir | 1.39 Å | 5WQ2 | 5WQ2 | 5WQ2 | 5WQ2 | 5WQ2 | 5WQ2 | |
| Coxsackievirus-type picornain 3C ( human enterovirus B) | ||||||||
| complex with rupintrivir (ag7088) | 1.50 Å | 3RUO | 3RUO | 3RUO | 3RUO | 3RUO | 3RUO | |
| human rhinovirus 2-type picornain 3C ( human rhinovirus 2) | ||||||||
| complex with AG7088 inhibitor | 1.85 Å | 1CQQ | 1CQQ | 1CQQ | 1CQQ | 1CQQ | 1CQQ | Matthews et al., 1999 |
