Structure for PPACK (S01.217 inhibitor)

PDB	Organism	Resolution	Comment
1ABJ	Homo sapiens	2.40 Å	complex with D-Phe-Pro-Arg chloromethylketone
Catalytic residues are shown in ball-and-stick representation: His406 in purple, Asp462 in pink and Ser568 in orange. The N-terminal light chain is shown in yellow. D-Phe-Pro-Arg-chloromethane is shown in grey in ball-and-stick representation.

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TERTIARY STRUCTURE DATA
Comment	Resolution	PDB	PDBe	SCOP	CATH	PDBSum	Proteopedia	Reference
thrombin ( Homo sapiens)
complex with D-Phe-Pro-Arg chloromethylketone	2.40 Å	1ABJ	1ABJ	1ABJ	1ABJ	1ABJ	1ABJ	Qiu et al., 1992
complex with hirugen and phenylmethylenecarboxy-(methyleneamino-formyl-diphenylmethyl)methy-pro-boroval	2.10 Å	1AIX	1AIX	1AIX	1AIX	1AIX	1AIX	Bode et al., 1992
alpha-thrombin; complex with des-Asp55 hirudin and D-Phe-Pro-Arg-chloromethylketone	3.00 Å	1DWE	1DWE	1DWE	1DWE	1DWE	1DWE	Banner & Hadvary, 1991
fast form mutant Arg77Ala; complex with PPACK	1.91 Å	1SFQ	1SFQ	1SFQ	1SFQ	1SFQ	1SFQ
slow form; complex with PPACK	1.55 Å	1SHH	1SHH	1SHH	1SHH	1SHH	1SHH
anticoagulant mutant Trp215Ala/Glu217Ala; complex with PPACK	2.40 Å	1TQ7	1TQ7	1TQ7	1TQ7	1TQ7	1TQ7
Gly193Ala mutant; complex with PPACK	2.00 Å	1Z8I	1Z8I	1Z8I	1Z8I	1Z8I	1Z8I
Cys191Ala-Cys220Ala mutant; complex with the inhibitor PPACK	1.80 Å	2PGQ	2PGQ	2PGQ	2PGQ	2PGQ	2PGQ
Ser195Thr mutant; complex with PPACK	1.84 Å	4RKO	4RKO	4RKO	4RKO	4RKO	4RKO
coagulation factor IXa ( Homo sapiens)
Lys98Thr variant; complex with PPACK	1.30 Å	5JB9	5JB9	5JB9	5JB9	5JB9	5JB9
Val16Ile/Lys98Thr/Tyr177Thr/Ile212Val variant; complex with PPACK	1.40 Å	5JBA	5JBA	5JBA	5JBA	5JBA	5JBA
Val16Ile/Lys98Thr/Tyr177Thr/Ile213val variant; complex with PPACK	1.90 Å	5JBC	5JBC	5JBC	5JBC	5JBC	5JBC
thrombin ( Homo sapiens)
Trp215Ala/Glu217Ala mutant fused to EGF456 of thrombomodulin via a 31-residue linker; complex with PPACK	2.34 Å	5TO3	5TO3	5TO3	5TO3	5TO3	5TO3