Structure for inhibitor I13.001: eglin c

Summary Alignment Sequences Sequence features Distribution Structure Literature

 

PDB Organism Resolution Comment
1EGP Hirudo medicinalis 2.00 Å cleaved at reactive centre
Only the inhibitor molecule is shown. The reactive site residue Leu45 is shown in ball-and-stick representation in green.
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1MEE_I Hirudo medicinalis 2.00 Å complex with subtilisin
Only the inhibitor molecule is shown. The reactive site residue Leu45 is shown in ball-and-stick representation in green.
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TERTIARY STRUCTURE DATA
Comment Resolution PDB PDBe SCOP CATH PDBSum Proteopedia Reference
Hirudo medicinalis
complex with chymotrypsin A 2.00 Å 1ACB 1ACB 1ACB 1ACB 1ACB 1ACB Frigerio et al., 1992
complex with subtilisin Carlsberg 1.20 Å 1CSE 1CSE 1CSE 1CSE 1CSE 1CSE Bode et al., 1987
NMR structure 0.00 Å 1EGL 1EGL 1EGL 1EGL 1EGL 1EGL Hyberts et al., 1992
cleaved at reactive centre 2.00 Å 1EGP 1EGP 1EGP 1EGP 1EGP 1EGP Betzel et al., 1993
complex with subtilisin 2.00 Å 1MEE 1MEE 1MEE 1MEE 1MEE 1MEE Dauter et al., 1991
complex with subtilisin BPN' 2.10 Å 1SBN 1SBN 1SBN 1SBN 1SBN 1SBN Heinz et al., 1991
complex with subtilisin BPN' 2.40 Å 1SIB 1SIB 1SIB 1SIB 1SIB 1SIB Heinz et al., 1991
complex with thermitase 2.20 Å 1TEC 1TEC 1TEC 1TEC 1TEC 1TEC Gros et al., 1989
N-acetyl eglin C; complex with subtilisin Carlsberg 1.80 Å 2SEC 2SEC 2SEC 2SEC 2SEC 2SEC McPhalen & James, 1988
complex with thermitase 1.98 Å 2TEC 2TEC 2TEC 2TEC 2TEC 2TEC Gros et al., 1989
complex with thermitase 2.00 Å 3TEC 3TEC 3TEC 3TEC 3TEC 3TEC Gros et al., 1991
mature  inhibitor 1.78 Å 4B1T 4B1T 4B1T 4B1T 4B1T 4B1T Menzel et al., 2014
mature  inhibitor 1.89 Å 4B2A 4B2A 4B2A 4B2A 4B2A 4B2A Menzel et al., 2014
mature  inhibitor 1.36 Å 4B2B 4B2B 4B2B 4B2B 4B2B 4B2B Menzel et al., 2014
mature  inhibitor 1.43 Å 4B2C 4B2C 4B2C 4B2C 4B2C 4B2C Menzel et al., 2014
complex with chymotrypsin C 1.90 Å 4H4F 4H4F 4H4F 4H4F 4H4F 4H4F Batra et al., 2013