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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL2337
Target Type SINGLE PROTEIN
Preferred Name Glycine transporter 1
Synonyms GlyT-1 | GlyT1 | SLC6A9 | Sodium- and chloride-dependent glycine transporter 1 | Solute carrier family 6 member 9
Organism Homo sapiens
Species Group No
Protein Target Classification
  • transporter > electrochemical transporter > slc superfamily of solute carriers > slc06 neurotransmitter transporter family

Target Components

Component Description Relationship Accession
Sodium- and chloride-dependent glycine transporter 1 SINGLE PROTEIN P48067

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000196517
Ensembl ENSG00000196517
GO Cellular Component GO:0005624 (membrane fraction)
GO:0005887 (integral to plasma membrane)
GO Molecular Function GO:0005328 (neurotransmitter:sodium symporter activity)
GO:0015375 (glycine:sodium symporter activity)
Wikipedia Glycine_transporter_1

Target Cross References - Protein

Human Protein Atlas ENSG00000196517
Guide to Pharmacology 935 (GlyT1)
PharmGKB PA35916
Reactome REACT_15518 (Transmembrane transport of small molecules.)
REACT_20679 (Amine compound SLC transporters.)
UniProt A6NDH1 A6NII2 A6NNZ8 P48067 Q5TAB8 Q5TAB9 Q5TAC0

Target Cross References - Domain

InterPro IPR000175 (Na/ntran_symport.)
IPR003028 (Na/ntran_symport_glycine_GLY1.)
Pfam PF00209 (SNF)
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