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CHEBI:77402 - EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor
| ChEBI ID | CHEBI:77402 |
| ChEBI Name | EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor |
| Stars | |
| Definition | An EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of trypanothione-disulfide reductase (EC 1.8.1.12). |
| Last Modified | 16 February 2017 |
| Submitter | Gareth Owen |
| Wikipedia |
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| ChEBI Ontology |
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| Outgoing Relation(s) |
| EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor (CHEBI:77402) is a EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD+ or NADP+ as acceptor) inhibitor (CHEBI:76869) |
| Incoming Relation(s) |
| citalopram (CHEBI:3723) has role EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor (CHEBI:77402) |
| clomipramine (CHEBI:47780) has role EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor (CHEBI:77402) |
| ebselen (CHEBI:77543) has role EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor (CHEBI:77402) |
| quinacrine (CHEBI:8711) has role EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor (CHEBI:77402) |
| thioridazine (CHEBI:9566) has role EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor (CHEBI:77402) |
| trifluoperazine (CHEBI:45951) has role EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor (CHEBI:77402) |
| EC 1.8.1.4 (dihydrolipoyl dehydrogenase) inhibitor (CHEBI:134545) is a EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor (CHEBI:77402) |
| Synonyms | Source |
|---|---|
| EC 1.8.1.12 inhibitor | ChEBI |
| EC 1.8.1.12 inhibitors | ChEBI |
| EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitors | ChEBI |
| N1,N8-bis(glutathionyl)spermidine reductase inhibitor | ChEBI |
| N1,N8-bis(glutathionyl)spermidine reductase inhibitors | ChEBI |
| NADPH2:trypanothione oxidoreductase inhibitor | ChEBI |
| Manual Xrefs | Databases |
|---|---|
| Trypanothione-disulfide_reductase | Wikipedia |