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CHEBI:47780 - clomipramine
| Formula | C19H23ClN2 |
| Net Charge | 0 |
| Average Mass | 314.860 |
| Monoisotopic Mass | 314.15498 |
| SMILES | CN(C)CCCN1c2ccccc2CCc2ccc(Cl)cc21 |
| InChI | InChI=1S/C19H23ClN2/c1-21(2)12-5-13-22-18-7-4-3-6-15(18)8-9-16-10-11-17(20)14-19(16)22/h3-4,6-7,10-11,14H,5,8-9,12-13H2,1-2H3 |
| InChIKey | GDLIGKIOYRNHDA-UHFFFAOYSA-N |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | anticoronaviral agent Any antiviral agent which inhibits the activity of coronaviruses. serotonergic antagonist Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists. serotonin uptake inhibitor A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent. EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor An EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of trypanothione-disulfide reductase (EC 1.8.1.12). |
| Applications: | anxiolytic drug Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. antidepressant Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. serotonergic antagonist Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists. serotonin uptake inhibitor A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent. antipsychotic agent Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| clomipramine (CHEBI:47780) has functional parent imipramine (CHEBI:47499) |
| clomipramine (CHEBI:47780) has role anticoronaviral agent (CHEBI:149553) |
| clomipramine (CHEBI:47780) has role antidepressant (CHEBI:35469) |
| clomipramine (CHEBI:47780) has role antipsychotic agent (CHEBI:35476) |
| clomipramine (CHEBI:47780) has role anxiolytic drug (CHEBI:35474) |
| clomipramine (CHEBI:47780) has role EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor (CHEBI:77402) |
| clomipramine (CHEBI:47780) has role serotonergic antagonist (CHEBI:48279) |
| clomipramine (CHEBI:47780) has role serotonergic drug (CHEBI:48278) |
| clomipramine (CHEBI:47780) has role serotonin uptake inhibitor (CHEBI:50949) |
| clomipramine (CHEBI:47780) is a dibenzoazepine (CHEBI:47804) |
| clomipramine (CHEBI:47780) is a dibenzooxazepine (CHEBI:53802) |
| clomipramine (CHEBI:47780) is a organic molecular entity (CHEBI:50860) |
| clomipramine (CHEBI:47780) is conjugate base of clomipramine(1+) (CHEBI:64209) |
| Incoming Relation(s) |
| clomipramine(1+) (CHEBI:64209) is conjugate acid of clomipramine (CHEBI:47780) |
| IUPAC Name |
|---|
| 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine |
| INN | Source |
|---|---|
| clomipramina | WHO MedNet |
| Synonyms | Source |
|---|---|
| 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethyl-1-propanamine | NIST Chemistry WebBook |
| 3-(3-CHLORO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N,N-DIMETHYLPROPAN-1-AMINE | PDBeChem |
| 3-chloro-iminodibenzyl | ChEMBL |
| 3-chloroimipramine | ChemIDplus |
| Anapramine | ChEMBL |
| chlorimipramine | NIST Chemistry WebBook |
| Citations |
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