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CHEBI:76674 - phosphorothioate oligonucleotide
| ChEBI ID | CHEBI:76674 |
| ChEBI Name | phosphorothioate oligonucleotide |
| Stars | |
| Definition | An oligonucleotide in which one of the non-bridging oxygens in each phosphodiester linkage has been replaced by sulfur. The main application of phosphorothioate linkages in an oligonucleotide is to protect the oligonucleotide from nuclease degradation. |
| Last Modified | 16 December 2013 |
| Submitter | Marcus Ennis |
| Wikipedia |
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| ChEBI Ontology |
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| Outgoing Relation(s) |
| phosphorothioate oligonucleotide (CHEBI:76674) is a oligonucleotide (CHEBI:7754) |
| Incoming Relation(s) |
| 5'-AsGsCsCsGsCsGsAsCsTsTsCsTsAsGsAsCsT-3' (CHEBI:76703) is a phosphorothioate oligonucleotide (CHEBI:76674) |
| 5'-CsGsGsCsTsCsCsAsTsGsTsAsCsAsGsCsAsTsGsCsG-3' (CHEBI:76701) is a phosphorothioate oligonucleotide (CHEBI:76674) |
| 5'-GsCsAsGsTsCsTsAsTsTsAsCsTsGsTsGsCsGsAsGsA-3' (CHEBI:76700) is a phosphorothioate oligonucleotide (CHEBI:76674) |
| 5'-GsCsCsGsAsGsGsTsCsCsAsTsGsTsCsGsTsAsCsGsC-3' (CHEBI:76689) is a phosphorothioate oligonucleotide (CHEBI:76674) |
| 5'-GsCsGsTsAsCsGsAsCsAsTsGsGsAsCsCsTsCsGsGsC-3' (CHEBI:76702) is a phosphorothioate oligonucleotide (CHEBI:76674) |
| 5'-TsGsTsGsGsGsTsTsAsAsGsAsCsTsTsTsTsTsAsCsC-3' (CHEBI:76690) is a phosphorothioate oligonucleotide (CHEBI:76674) |
| d(Gs)19dG (CHEBI:76705) is a phosphorothioate oligonucleotide (CHEBI:76674) |
| Synonyms | Source |
|---|---|
| S-oligos | ChEBI |
| phosphorothioate oligonucleotides | ChEBI |
| S-oligo | ChEBI |
| PS DNA | ChEBI |
| phosphorothioate DNA | ChEBI |
| OPS | ChEBI |
| Manual Xrefs | Databases |
|---|---|
| Oligonucleotide_synthesis#Oligonucleotide_phosphorothioates_and_their_synthesis | Wikipedia |
| Citations |
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