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CHEBI:76701 - 5'-CsGsGsCsTsCsCsAsTsGsTsAsCsAsGsCsAsTsGsCsG-3'

ChEBI IDCHEBI:76701
ChEBI Name5'-CsGsGsCsTsCsCsAsTsGsTsAsCsAsGsCsAsTsGsCsG-3'
Stars
DefinitionA phosphorothioate oligonucleotide consisting of six deoxyguanosine, seven deoxycytidine, four deoxyadenosine and four thymidine residues connected by 3'→5' phosphorothioate linkages in the sequence C-G-G-C-T-C-C-A-T-G-T-A-C-A-G-C-A-T-G-C-G.
Last Modified16 December 2013
SubmitterMarcus Ennis
DownloadsMolfile
FormulaC203H258N79O106P21S21
Net Charge0
Average Mass6824.605
Monoisotopic Mass6819.58514
SMILESCc1cn([C@H]2C[C@H](OP(=O)(S)OC[C@H]3O[C@@H](n4ccc(N)nc4=O)C[C@@H]3OP(=O)(S)OC[C@H]3O[C@@H](n4ccc(N)nc4=O)C[C@@H]3OP(=O)(S)OC[C@H]3O[C@@H](n4cnc5c(N)ncnc54)C[C@@H]3OP(=O)(S)OC[C@H]3O[C@@H](n4cc(C)c(=O)nc4=O)C[C@@H]3OP(=O)(S)OC[C@H]3O[C@@H](n4cnc5c(=O)nc(N)nc54)C[C@@H]3OP(=O)(S)OC[C@H]3O[C@@H](n4cc(C)c(=O)nc4=O)C[C@@H]3OP(=O)(S)OC[C@H]3O[C@@H](n4cnc5c(N)ncnc54)C[C@@H]3OP(=O)(S)OC[C@H]3O[C@@H](n4ccc(N)nc4=O)C[C@@H]3OP(=O)(S)OC[C@H]3O[C@@H](n4cnc5c(N)ncnc54)C[C@@H]3OP(=O)(S)OC[C@H]3O[C@@H](n4cnc5c(=O)nc(N)nc54)C[C@@H]3OP(=O)(S)OC[C@H]3O[C@@H](n4ccc(N)nc4=O)C[C@@H]3OP(=O)(S)OC[C@H]3O[C@@H](n4cnc5c(N)ncnc54)C[C@@H]3OP(=O)(S)OC[C@H]3O[C@@H](n4cc(C)c(=O)nc4=O)C[C@@H]3OP(=O)(S)OC[C@H]3O[C@@H](n4cnc5c(=O)nc(N)nc54)C[C@@H]3OP(=O)(S)OC[C@H]3O[C@@H](n4ccc(N)nc4=O)C[C@@H]3OP(=O)(S)OC[C@H]3O[C@@H](n4cnc5c(=O)nc(N)nc54)C[C@@H]3OP(=O)(O)S)[C@@H](COP(=O)(S)O[C@H]3C[C@H](n4ccc(N)nc4=O)O[C@@H]3COP(=O)(S)O[C@H]3C[C@H](n4cnc5c(=O)nc(N)nc54)O[C@@H]3COP(=O)(S)O[C@H]3C[C@H](n4cnc5c(=O)nc(N)nc54)O[C@@H]3COP(=O)(S)O[C@H]3C[C@H](n4ccc(N)nc4=O)O[C@@H]3CO)O2)c(=O)nc1=O
InChIInChI=1S/C203H258N79O106P21S21/c1-79-40-269(200(301)258-177(79)284)139-27-91(112(354-139)52-335-393(310,414)372-87-23-135(265-15-8-128(207)242-196(265)297)352-110(87)50-333-403(320,424)386-102-38-151(281-77-237-161-175(281)250-191(219)256-185(161)292)367-124(102)64-346-409(326,430)388-99-35-148(278-74-234-158-172(278)247-188(216)253-182(158)289)363-120(99)60-328-390(307,411)369-83-19-132(347-104(83)44-283)262-12-5-125(204)239-193(262)294)376-397(314,418)330-47-107-86(22-134(349-107)264-14-7-127(206)241-195(264)296)371-392(309,413)329-46-106-88(24-136(348-106)266-16-9-129(208)243-197(266)298)373-394(311,415)339-56-116-96(32-144(359-116)274-70-230-154-164(212)222-66-226-168(154)274)381-405(322,426)337-54-114-94(30-142(356-114)272-43-82(4)180(287)261-203(272)304)379-400(317,421)344-62-122-103(39-152(365-122)282-78-238-162-176(282)251-192(220)257-186(162)293)387-407(324,428)338-55-115-92(28-140(357-115)270-41-80(2)178(285)259-201(270)302)377-398(315,419)342-59-119-95(31-143(362-119)273-69-229-153-163(211)221-65-225-167(153)273)380-401(318,422)331-48-109-89(25-137(351-109)267-17-10-130(209)244-198(267)299)374-396(313,417)341-58-118-98(34-146(361-118)276-72-232-156-166(214)224-68-228-170(156)276)383-408(325,429)345-63-123-101(37-150(366-123)280-76-236-160-174(280)249-190(218)255-184(160)291)385-404(321,425)334-51-111-90(26-138(353-111)268-18-11-131(210)245-199(268)300)375-395(312,416)340-57-117-97(33-145(360-117)275-71-231-155-165(213)223-67-227-169(155)275)382-406(323,427)336-53-113-93(29-141(355-113)271-42-81(3)179(286)260-202(271)303)378-399(316,420)343-61-121-100(36-149(364-121)279-75-235-159-173(279)248-189(217)254-183(159)290)384-402(319,423)332-49-108-85(21-133(350-108)263-13-6-126(205)240-194(263)295)370-391(308,412)327-45-105-84(368-389(305,306)410)20-147(358-105)277-73-233-157-171(277)246-187(215)252-181(157)288/h5-18,40-43,65-78,83-124,132-152,283H,19-39,44-64H2,1-4H3,(H,307,411)(H,308,412)(H,309,413)(H,310,414)(H,311,415)(H,312,416)(H,313,417)(H,314,418)(H,315,419)(H,316,420)(H,317,421)(H,318,422)(H,319,423)(H,320,424)(H,321,425)(H,322,426)(H,323,427)(H,324,428)(H,325,429)(H,326,430)(H2,204,239,294)(H2,205,240,295)(H2,206,241,296)(H2,207,242,297)(H2,208,243,298)(H2,209,244,299)(H2,210,245,300)(H2,211,221,225)(H2,212,222,226)(H2,213,223,227)(H2,214,224,228)(H,258,284,301)(H,259,285,302)(H,260,286,303)(H,261,287,304)(H2,305,306,410)(H3,215,246,252,288)(H3,216,247,253,289)(H3,217,248,254,290)(H3,218,249,255,291)(H3,219,250,256,292)(H3,220,251,257,293)/t83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104+,105+,106+,107+,108+,109+,110+,111+,112+,113+,114+,115+,116+,117+,118+,119+,120+,121+,122+,123+,124+,132+,133+,134+,135+,136+,137+,138+,139+,140+,141+,142+,143+,144+,145+,146+,147+,148+,149+,150+,151+,152+,390?,391?,392?,393?,394?,395?,396?,397?,398?,399?,400?,401?,402?,403?,404?,405?,406?,407?,408?,409?/m0/s1
InChIKeyYVDMEHLUTRAFCB-YVIRUZHPSA-N
Roles Classification
Biological Roles:
antisense oligonucleotide  A synthetic oligonucleotide whose base sequence is complementary to a gene's messenger RNA (mRNA) and which will bind with the mRNA inactivating it.
antigen  Any substance that stimulates an immune response in the body, such as through antibody production or by presentation to a T-cell receptor after binding to a major histocompability complex (MHC).
ChEBI Ontology
Outgoing Relation(s)
5'-CsGsGsCsTsCsCsAsTsGsTsAsCsAsGsCsAsTsGsCsG-3' (CHEBI:76701) has role antigen (CHEBI:59132)
5'-CsGsGsCsTsCsCsAsTsGsTsAsCsAsGsCsAsTsGsCsG-3' (CHEBI:76701) has role antisense oligonucleotide (CHEBI:76720)
5'-CsGsGsCsTsCsCsAsTsGsTsAsCsAsGsCsAsTsGsCsG-3' (CHEBI:76701) is a phosphorothioate oligonucleotide (CHEBI:76674)
Synonyms  Source
phosphorothioate-linked 5'-CGG CTC CAT GTA CAG CAT GCG-3'ChEBI
phosphorothioate-linked 5'-CGGCTCCATGTACAGCATGCG-3'ChEBI
[All-PS]-d(CGGCTCCATGTACAGCATGCG)ChEBI
d[CPSGPSGPSCPSTPSCPSCPSAPSTPSGPSTPSAPSCPSAPSGPSCPSAPSTPSPSGPSCPSG]ChEBI
[PS]-5'-CGGCTCCATGTACAGCATGCG-3'ChEBI
Citations