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CHEBI:76702 - 5'-GsCsGsTsAsCsGsAsCsAsTsGsGsAsCsCsTsCsGsGsC-3'

ChEBI IDCHEBI:76702
ChEBI Name5'-GsCsGsTsAsCsGsAsCsAsTsGsGsAsCsCsTsCsGsGsC-3'
Stars
DefinitionA phosphorothioate oligonucleotide consisting of seven deoxyguanosine, seven deoxycytidine, four deoxyadenosine and three thymidine residues connected by 3'→5' phosphorothioate linkages in the sequence G-C-G-T-A-C-G-A-C-A-T-G-G-A-C-C-T-C-G-G-C.
Last Modified16 December 2013
SubmitterMarcus Ennis
DownloadsMolfile
FormulaC203H257N82O105P21S21
Net Charge0
Average Mass6849.619
Monoisotopic Mass6844.59162
SMILESCc1cn([C@H]2C[C@H](OP(=O)(S)OC[C@H]3O[C@@H](n4ccc(N)nc4=O)C[C@@H]3OP(=O)(S)OC[C@H]3O[C@@H](n4cnc5c(=O)nc(N)nc54)C[C@@H]3OP(=O)(S)OC[C@H]3O[C@@H](n4cnc5c(=O)nc(N)nc54)C[C@@H]3OP(=O)(S)OC[C@H]3O[C@@H](n4ccc(N)nc4=O)C[C@@H]3OP(=O)(O)S)[C@@H](COP(=O)(S)O[C@H]3C[C@H](n4ccc(N)nc4=O)O[C@@H]3COP(=O)(S)O[C@H]3C[C@H](n4ccc(N)nc4=O)O[C@@H]3COP(=O)(S)O[C@H]3C[C@H](n4cnc5c(N)ncnc54)O[C@@H]3COP(=O)(S)O[C@H]3C[C@H](n4cnc5c(=O)nc(N)nc54)O[C@@H]3COP(=O)(S)O[C@H]3C[C@H](n4cnc5c(=O)nc(N)nc54)O[C@@H]3COP(=O)(S)O[C@H]3C[C@H](n4cc(C)c(=O)nc4=O)O[C@@H]3COP(=O)(S)O[C@H]3C[C@H](n4cnc5c(N)ncnc54)O[C@@H]3COP(=O)(S)O[C@H]3C[C@H](n4ccc(N)nc4=O)O[C@@H]3COP(=O)(S)O[C@H]3C[C@H](n4cnc5c(N)ncnc54)O[C@@H]3COP(=O)(S)O[C@H]3C[C@H](n4cnc5c(=O)nc(N)nc54)O[C@@H]3COP(=O)(S)O[C@H]3C[C@H](n4ccc(N)nc4=O)O[C@@H]3COP(=O)(S)O[C@H]3C[C@H](n4cnc5c(N)ncnc54)O[C@@H]3COP(=O)(S)O[C@H]3C[C@H](n4cc(C)c(=O)nc4=O)O[C@@H]3COP(=O)(S)O[C@H]3C[C@H](n4cnc5c(=O)nc(N)nc54)O[C@@H]3COP(=O)(S)O[C@H]3C[C@H](n4ccc(N)nc4=O)O[C@@H]3COP(=O)(S)O[C@H]3C[C@H](n4cnc5c(=O)nc(N)nc54)O[C@@H]3CO)O2)c(=O)nc1=O
InChIInChI=1S/C203H257N82O105P21S21/c1-78-39-272(201(304)262-177(78)287)137-26-89(378-400(317,421)332-46-106-86(23-134(353-106)269-15-8-127(208)245-198(269)301)376-398(315,419)345-59-119-99(36-148(366-119)283-75-238-159-174(283)252-191(219)259-184(159)294)389-410(327,431)347-61-121-96(33-145(368-121)280-72-235-156-171(280)249-188(216)256-181(156)291)385-393(310,414)329-43-103-82(370-391(307,308)412)19-130(350-103)265-11-4-123(204)241-194(265)297)110(357-137)50-336-395(312,416)373-85-22-133(268-14-7-126(207)244-197(268)300)352-105(85)45-331-394(311,415)372-84-21-132(267-13-6-125(206)243-196(267)299)354-107(84)47-333-404(321,425)382-93-30-141(276-68-231-152-163(212)223-64-227-167(152)276)363-116(93)56-342-409(326,430)388-101-38-150(285-77-240-161-176(285)254-193(221)261-186(161)296)369-122(101)62-348-411(328,432)390-100-37-149(284-76-239-160-175(284)253-192(220)260-185(160)295)367-120(100)60-346-402(319,423)380-91-28-139(274-41-80(3)179(289)264-203(274)306)358-111(91)51-337-406(323,427)384-95-32-143(278-70-233-154-165(214)225-66-229-169(154)278)360-113(95)53-339-396(313,417)375-87-24-135(270-16-9-128(209)246-199(270)302)355-108(87)48-334-405(322,426)383-94-31-142(277-69-232-153-164(213)224-65-228-168(153)277)362-115(94)55-341-408(325,429)387-98-35-147(282-74-237-158-173(282)251-190(218)258-183(158)293)365-118(98)58-344-399(316,420)377-88-25-136(271-17-10-129(210)247-200(271)303)356-109(88)49-335-403(320,424)381-92-29-140(275-67-230-151-162(211)222-63-226-166(151)275)361-114(92)54-340-401(318,422)379-90-27-138(273-40-79(2)178(288)263-202(273)305)359-112(90)52-338-407(324,428)386-97-34-146(281-73-236-157-172(281)250-189(217)257-182(157)292)364-117(97)57-343-397(314,418)374-83-20-131(266-12-5-124(205)242-195(266)298)351-104(83)44-330-392(309,413)371-81-18-144(349-102(81)42-286)279-71-234-155-170(279)248-187(215)255-180(155)290/h4-17,39-41,63-77,81-122,130-150,286H,18-38,42-62H2,1-3H3,(H,309,413)(H,310,414)(H,311,415)(H,312,416)(H,313,417)(H,314,418)(H,315,419)(H,316,420)(H,317,421)(H,318,422)(H,319,423)(H,320,424)(H,321,425)(H,322,426)(H,323,427)(H,324,428)(H,325,429)(H,326,430)(H,327,431)(H,328,432)(H2,204,241,297)(H2,205,242,298)(H2,206,243,299)(H2,207,244,300)(H2,208,245,301)(H2,209,246,302)(H2,210,247,303)(H2,211,222,226)(H2,212,223,227)(H2,213,224,228)(H2,214,225,229)(H,262,287,304)(H,263,288,305)(H,264,289,306)(H2,307,308,412)(H3,215,248,255,290)(H3,216,249,256,291)(H3,217,250,257,292)(H3,218,251,258,293)(H3,219,252,259,294)(H3,220,253,260,295)(H3,221,254,261,296)/t81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102+,103+,104+,105+,106+,107+,108+,109+,110+,111+,112+,113+,114+,115+,116+,117+,118+,119+,120+,121+,122+,130+,131+,132+,133+,134+,135+,136+,137+,138+,139+,140+,141+,142+,143+,144+,145+,146+,147+,148+,149+,150+,392?,393?,394?,395?,396?,397?,398?,399?,400?,401?,402?,403?,404?,405?,406?,407?,408?,409?,410?,411?/m0/s1
InChIKeyFVYOTBSSVWPIJC-WSDFBDMOSA-N
Roles Classification
Biological Roles:
antisense oligonucleotide  A synthetic oligonucleotide whose base sequence is complementary to a gene's messenger RNA (mRNA) and which will bind with the mRNA inactivating it.
antigen  Any substance that stimulates an immune response in the body, such as through antibody production or by presentation to a T-cell receptor after binding to a major histocompability complex (MHC).
ChEBI Ontology
Outgoing Relation(s)
5'-GsCsGsTsAsCsGsAsCsAsTsGsGsAsCsCsTsCsGsGsC-3' (CHEBI:76702) has role antigen (CHEBI:59132)
5'-GsCsGsTsAsCsGsAsCsAsTsGsGsAsCsCsTsCsGsGsC-3' (CHEBI:76702) has role antisense oligonucleotide (CHEBI:76720)
5'-GsCsGsTsAsCsGsAsCsAsTsGsGsAsCsCsTsCsGsGsC-3' (CHEBI:76702) is a phosphorothioate oligonucleotide (CHEBI:76674)
Synonyms  Source
phosphorothioate-linked 5'-GCG TAC GAC ATG GAC CTC GGC-3'ChEBI
d[GPSCPSGPSTPSAPSCPSGPSAPSCPSAPSTPSGPSGPSAPSCPSCPSTPSCPSPSGPSGPSC]ChEBI
phosphorothioate-linked 5'-GCGTACGACATGGACCTCGGC-3'ChEBI
[All-PS]-d(GCGTACGACATGGACCTCGGC)ChEBI
[PS]-5'-GCGTACGACATGGACCTCGGC-3'ChEBI
Citations