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CHEBI:50781 - EC 1.3.1.22 [3-oxo-5α-steroid 4-dehydrogenase (NADP+)] inhibitor
| ChEBI ID | CHEBI:50781 |
| ChEBI Name | EC 1.3.1.22 [3-oxo-5α-steroid 4-dehydrogenase (NADP+)] inhibitor |
| Stars | |
| ASCII Name | EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor |
| Definition | An EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of of 3-oxo-5α-steroid 4-dehydrogenase (NADP+), EC 1.3.1.22, the enzyme which converts testosterone (CHEBI:17347) into the more potent androgen 5α-dihydrotestosterone. |
| Last Modified | 7 April 2016 |
| Submitter | Marcus Ennis |
| Wikipedia |
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| ChEBI Ontology |
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| Outgoing Relation(s) |
| EC 1.3.1.22 [3-oxo-5α-steroid 4-dehydrogenase (NADP+)] inhibitor (CHEBI:50781) is a EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD+ or NADP+ as acceptor) inhibitor (CHEBI:76857) |
| Incoming Relation(s) |
| 3',4',5-trihydroxy-3,7-dimethoxyflavone (CHEBI:18010) has role EC 1.3.1.22 [3-oxo-5α-steroid 4-dehydrogenase (NADP+)] inhibitor (CHEBI:50781) |
| 3',4',7-trihydroxyisoflavone (CHEBI:50399) has role EC 1.3.1.22 [3-oxo-5α-steroid 4-dehydrogenase (NADP+)] inhibitor (CHEBI:50781) |
| 4-pregnen-20,21-diol-3-one (CHEBI:87841) has role EC 1.3.1.22 [3-oxo-5α-steroid 4-dehydrogenase (NADP+)] inhibitor (CHEBI:50781) |
| dutasteride (CHEBI:521033) has role EC 1.3.1.22 [3-oxo-5α-steroid 4-dehydrogenase (NADP+)] inhibitor (CHEBI:50781) |
| finasteride (CHEBI:5062) has role EC 1.3.1.22 [3-oxo-5α-steroid 4-dehydrogenase (NADP+)] inhibitor (CHEBI:50781) |
| impatienol (CHEBI:72634) has role EC 1.3.1.22 [3-oxo-5α-steroid 4-dehydrogenase (NADP+)] inhibitor (CHEBI:50781) |
| prunetin (CHEBI:8600) has role EC 1.3.1.22 [3-oxo-5α-steroid 4-dehydrogenase (NADP+)] inhibitor (CHEBI:50781) |
| Synonyms | Source |
|---|---|
| 3-oxo-5α-steroid 4-dehydrogenase inhibitor | ChEBI |
| 3-oxo-5α-steroid 4-dehydrogenase inhibitors | ChEBI |
| 3-oxo-5α-steroid 4-dehydrogenase (NADP+) (EC 1.3.1.22) inhibitor | ChEBI |
| 3-oxo-5α-steroid 4-dehydrogenase (NADP+) (EC 1.3.1.22) inhibitors | ChEBI |
| 3-oxo-5α-steroid 4-dehydrogenase (NADP+) inhibitor | ChEBI |
| 3-oxo-5α-steroid 4-dehydrogenase (NADP+) inhibitors | ChEBI |
| Manual Xrefs | Databases |
|---|---|
| 5-alpha-reductase_inhibitor | Wikipedia |