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CHEBI:37532 - phorbol ester

ChEBI IDCHEBI:37532
ChEBI Namephorbol ester
Stars
DefinitionEsters of phorbol, originally found in croton oil (from Croton tiglium, of the family Euphorbiaceae). A number of phorbol esters possess activity as tumour promoters and activate the mechanisms associated with cell growth. Some of these are used in experiments as activators of protein kinase C.
Last Modified30 November 2022
SubmitterKirill Degtyarenko
ChEBI Ontology
Outgoing Relation(s)
phorbol ester (CHEBI:37532) has functional parent phorbol (CHEBI:8116)
phorbol ester (CHEBI:37532) is a carboxylic ester (CHEBI:33308)
phorbol ester (CHEBI:37532) is a diterpenoid (CHEBI:23849)
phorbol ester (CHEBI:37532) is a tetracyclic diterpenoid (CHEBI:52557)
Incoming Relation(s)
[(1S,6R,10S,13S,14R,15R)-1,6-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-14-[(E)-2-methylbut-2-enoyl]oxy-5-oxo-13-tetracyclo[8.5.0.02,6.011,13]pentadeca-3,8-dienyl] 2-methylbutanoate (CHEBI:182074) is a phorbol ester (CHEBI:37532)
[1,6-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-13-(2-methylpropanoyloxy)-5-oxo-14-tetracyclo[8.5.0.02,6.011,13]pentadeca-3,8-dienyl] (E)-2-methylbut-2-enoate (CHEBI:181555) is a phorbol ester (CHEBI:37532)
[13-acetyloxy-1,6-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-5-oxo-14-tetracyclo[8.5.0.02,6.011,13]pentadeca-3,8-dienyl] (E)-2-methylbut-2-enoate (CHEBI:181595) is a phorbol ester (CHEBI:37532)
12-deoxyphorbaldehyde-13-hexadecanoate (CHEBI:69821) is a phorbol ester (CHEBI:37532)
12-deoxyphorbol 20-acetate 13-(2-methylbutanoate) (CHEBI:4660) is a phorbol ester (CHEBI:37532)
12-deoxyphorbol-13-(3E,5E-decadienoate) (CHEBI:65747) is a phorbol ester (CHEBI:37532)
12-deoxyphorbol-13-hexadecanoate (CHEBI:69820) is a phorbol ester (CHEBI:37532)
12-deoxyphorbol-13,20-diacetate (CHEBI:69819) is a phorbol ester (CHEBI:37532)
12-O-Decanoylphorbol-13-acetate (CHEBI:70537) is a phorbol ester (CHEBI:37532)
12b-O-[Deca-2Z,4E-dienoyl]-13a-isobutyl-5-ene-7-oxo-4b-phorbol (CHEBI:181979) is a phorbol ester (CHEBI:37532)
16-hydroxyphorbol 13-decanoate 12-palmitate (CHEBI:744) is a phorbol ester (CHEBI:37532)
4-deoxyphorbol 12-acetate 13-(2Z,4E,6E)-deca-2,4,6-trienoate (CHEBI:4941) is a phorbol ester (CHEBI:37532)
4α-phorbol 12,13-didecanoate (CHEBI:139299) is a phorbol ester (CHEBI:37532)
Candletoxin A (CHEBI:3352) is a phorbol ester (CHEBI:37532)
LSM-4341 (CHEBI:93813) is a phorbol ester (CHEBI:37532)
pedilstatin (CHEBI:743) is a phorbol ester (CHEBI:37532)
phorbol 12,13-dibutanoate (CHEBI:17598) is a phorbol ester (CHEBI:37532)
phorbol 13-acetate (CHEBI:45127) is a phorbol ester (CHEBI:37532)
phorbol 13-acetate 12-myristate (CHEBI:37537) is a phorbol ester (CHEBI:37532)
phorbol 13-butanoate (CHEBI:17727) is a phorbol ester (CHEBI:37532)
phorbol 13-decanoate 12-tiglate (CHEBI:28366) is a phorbol ester (CHEBI:37532)
prostratin (CHEBI:69818) is a phorbol ester (CHEBI:37532)
rel-12-O-(4Z,7Z)-Deca-4,7-dienoylphorbol-13-acetate (CHEBI:70534) is a phorbol ester (CHEBI:37532)
rel-12-O-(4Z)-Deca-4-enoylphorbol-13-acetate (CHEBI:70535) is a phorbol ester (CHEBI:37532)
rel-12-O-Octanoylphorbol-13-acetate (CHEBI:70536) is a phorbol ester (CHEBI:37532)
rel-16-Angeloyloxy-13alpha-isobutanoyloxy-4beta,9alpha,20-trihydroxytiglia-1,5-diene-3,7-dione (CHEBI:67863) is a phorbol ester (CHEBI:37532)
rel-16-Angeloyloxy-13alpha-isobutanoyloxy-4beta,9alpha,7beta-trihydroxytiglia-1,5-dien-3-one (CHEBI:67864) is a phorbol ester (CHEBI:37532)
sapintoxin D (CHEBI:72442) is a phorbol ester (CHEBI:37532)
tigilanol tiglate (CHEBI:194146) is a phorbol ester (CHEBI:37532)
Synonym  Source
phorbol esterChEBI
Citations