The Electron Microscopy Data Bank (EMDB) is a public repository for cryogenic-sample Electron Microscopy (cryoEM) volumes and representative tomograms of macromolecular complexes and subcellular structures. It covers a variety of techniques, including single-particle analysis, helical reconstruction, electron tomography, subtomogram averaging, and electron crystallography. More...
As of 03 December 2025, EMDB contains 51919 entries (latest entries, trends).
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Q-score as a reliability measure for protein, nucleic acid and small-molecule atomic coordinate models derived from 3DEM maps
Grigore Pintilie, Chenghua Shao, Zhe Wang, Brian P Hudson, Justin W Flatt, Michael F Schmid, Kyle L Morris, Stephen K Burley, Wah Chiu. (2025) Acta Cryst D81: 410-422 doi: 10.1107/S2059798325005923
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A total of 2,540 respondants took the time to fill in this EMBL-EBI survey. We will learn how EMDB and other services like EMPIAR and PDB help you and this will help EMBL-EBI make the case for why open data resources are critical to life science research. Thank you for the incredible number of responses.
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We are delighted to share that EMDB has officially been elevated to a Core Data Resource by ELIXIR, recognising it as a European data resource of fundamental importance to the wider life-science community and the long-term preservation of biological data.
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Cryo-EM structure of COP9 signalosome deneddylation state with cullin-5
Focused map of COP9 signalosome precatalytic state with neddylated cullin-1
Cryo-EM structure of COP9 signalosome precatalytic state with neddylated cullin-1
Cryo-EM structure of COP9 signalosome deneddylation state of cullin-4A
Focused map of COP9 signalosome deneddylation complex with cullin-2
Cryo-EM structure of COP9 signalosome deneddylation complex with cullin-2
Focused map of COP9 signalosome deneddylation complex with neddylated cullin-3
Cryo-EM structure of COP9 signalosome deneddylation complex with cullin-3
Cryo-EM structure of COP9 signalosome precatalytic state with neddylated cullin-1
Cryo-EM structure of COP9 signalosome precatalytic state with neddylated cullin-2
Cryo-EM structure of COP9 signalosome precatalytic state with neddylated cullin-4A
1-methyl-pseudouridine L-21 ScaI Tetrahymena Ribozyme - extended conformation
Cryo-EM structure of COP9 signalosome precatalytic state with neddylated cullin-3
DDB1-CRBN with Ikaros(ZF2) and DEG-47: composite map and model submission
Cryo-EM structure of Candida albicans fluoride channel FEX in complex with Fab fragment
Cryo-EM structure of [Pen5]-urotensin (4-11)-bounded human Urotensin receptor (UTS2R)-Gq complex
Cryo-EM structure of NDUFA4 bound complex IV within the respirasome complex
Structure of the Human Peptide-Loading Complex Arrested by HCMV US6
cryoEM structure of ptuA-ptuB complex in Retron-Eco7 anti-phage system
Cryo-EM structure of alpha-synuclein fibrils formed in artificial cerebrospinal fluid (aCSF)
Cryo-ET reconstruction of a regenerating axon after axotomy showing polymerizing microtubules (primary mouse thalamus neuronal explant)
Cryo-ET reconstruction of a regenerating axon 24 h after axotomy (primary mouse thalamus neuronal explant)
Cryo-ET reconstruction of a regenerating axon after axotomy showing branching microtubules (primary mouse thalamus neuronal explant)
Cryo-ET reconstruction of a regenerating axon after axotomy showing branching microtubules (primary mouse thalamus neuronal explant, control)
Cryo-EM structure of conoid fiber from Toxoplasma gondii (24-nm repeat)
Cryo-ET subtomogram averaging of a stress fiber from a regenerating axon
Cryo-ET reconstruction of a regenerating axon 24 h after axotomy (primary mouse thalamus neuronal explant)
Cryo-EM structure of intraconoidal microtubule 1 (ICMT1) from Toxoplasma gondii (8-nm repeat)
Cryo-EM structure of the apical region of subpellicular microtubule (SPMT) from Toxoplasma gondii (8-nm repeat)
Cryo-EM structure of intraconoidal microtubule 2 (ICMT2) from Toxoplasma gondii (8-nm repeat)
FusA (ferredoxin receptor from Pectobacterium atrosepticum) in the presence of Ra-LPS
Molecular Architecture of Human Glycogen Debranching Enzyme: Insights into Glycogen Storage Disease III Pathogenesis
Cryo-EM structure of the PI4KA complex bound to an EFR3 interfering nanobody (F3IN)
Cryo-EM structure of CtpA from Helicobacter pylori in conformation I
Subtomogram average of the mtHsp60:mtHsp10 Football complex from HeLa
Subtomogram average of the mtHsp60:mtHsp10 half-football complex from HeLa
Cryo-EM structure of CtpA from Helicobacter pylori in an all-resting state
Cryo-EM map of carboxysomal midi-shell: T = 16 shell under C1 symmetry
Cryo-EM map of carboxysomal midi-shell: T = 9 shell under C1 symmetry
Cryo-EM structure of CtpA from Helicobacter pylori in conformation II
Cryo-EM structure of CtpA S300A/K325A/Q329A mutant from Helicobacter pylori
Cryo-EM structure of Adriforant-bound Histamine receptor 4 H4R at inactive state
Structure of the wild-type PSI-9VCPI supercomplex in Nannochloropsis oceanica
Structure of the wild-type PSI-8VCPI supercomplex in Nannochloropsis oceanica
Structure-Guided Design of Picomolar-level Macrocyclic TRPC5 Channel Inhibitors with Antidepressant Activity
Cryo-EM structure of Candida glabrata GPI mannosyltransferase I bound to Dol-P-Man
Omicron-specific ultra-potent SARS-CoV-2 neutralizing antibodies targeting the N1/N2 loop of Spike N-terminal domain
Cryo EM structure of RC-dLH complex model II from Gemmatimonas groenlandica
Structure of the HCV IRES-dependent 48S translation initiation complex with eIF5B and eIF3
Cryo-EM structure of the HCV IRES-dependently initiated CMV-stalled 80S ribosome (non-rotated state) in complexed with eIF3
Cryo-EM structure of the HCV IRES-dependently initiated CMV-stalled 80S ribosome (rotated state) in complexed with eIF3
The Cullin 2 RING VHL E3 ligase dimerized by the homoPROTAC CM11, C1 symmetry
Structure of the HCV IRES-dependent pre-48S translation initiation complex with eIF1A, eIF5B, and eIF3
Structure of the human 40S ribosome complexed with HCV IRES and eIF3
Structure of the human 40S ribosome complexed with HCV IRES, eIF1A and eIF3
RAD51 filament in complex with calcium and ATP bound by the RAD51AP1 C-terminus
RAD51 filament in complex with magnesium and ATP bound by the RAD51AP1 C-terminus
Cryo-EM Structure of Pig Ryanodine Receptor 1 R615C Mutant: Atorvastatin Bound Open Conformation Composite Map
The Kaggle CryoET Object Identification Challenge: first place 80S ribosome
Cryo-EM Structure of Rabbit Ryanodine Receptor 1: Atorvastatin Bound Closed Conformation Composite Map
Cryo-EM Structure of Rabbit Ryanodine Receptor 1: DMSO Control Composite Map
Human OCTN2 bound to ipratropium in an inward-facing conformation
The Kaggle CryoET Object Identification Challenge: ground truth 80S ribosome
Human IMPDH2 mutant - S160del, treated with GTP, ATP, IMP, and NAD+; interfacial octamer reconstruction
Human IMPDH2 mutant - S160del, treated with GTP, ATP, IMP, and NAD+; tetramer reconstruction
The Kaggle CryoET Object Identification Challenge: ground truth beta-galactosidase
The Kaggle CryoET Object Identification Challenge: first place beta-galactosidase
The Kaggle CryoET Object Identification Challenge: first place apo-ferritin
The Kaggle CryoET Object Identification Challenge: ground truth virus-like-particle
The Kaggle CryoET Object Identification Challenge: ground truth apo-ferritin
The Kaggle CryoET Object Identification Challenge: first place virus-like-particle
The Kaggle CryoET Object Identification Challenge: ground truth beta-amylase
The Kaggle CryoET Object Identification Challenge: ground truth thyroglobulin
The Kaggle CryoET Object Identification Challenge: first place thyroglobulin
The Kaggle CryoET Object Identification Challenge: first place beta-amylase
Cryo ET of Native Hippocampal Glutamatergic Synapses Using Dimeric AuNP Labeling
Cryo ET of Native Hippocampal Glutamatergic Synapses Using Dimeric AuNP Labeling 6
Cryo ET of Native Hippocampal Glutamatergic Synapses Using Dimeric AuNP Labeling 7
ECD focus refined map of Non-active state Gly/Glu/PS bound hGluN1a-2B NMDAR
Venezuelan Equine Encephalitis Virus in complex with the single domain antibody V2B3
Consensus map of Closed state Gly/Glu/24S-HC bound hGluN1a-2B NMDAR
Venezuelan Equine Encephalitis Virus in complex with the single domain antibody V3A8f
Cryo ET of Native Hippocampal Glutamatergic Synapses Using Dimeric AuNP Labeling 2
Cryo ET of Native Hippocampal Glutamatergic Synapses without AuNP label
Cryo ET of Native Hippocampal Glutamatergic Synapses Using Dimeric AuNP Labeling 5
ECD focused map of open state Gly/Glu/24S-HC bound hGluN1a-2B NMDAR
Cryo ET of Native Hippocampal Glutamatergic Synapses without AuNP label 3
Cryo ET of Native Hippocampal Glutamatergic Synapses Using Dimeric AuNP Labeling 4
Venezuelan Equine Encephalitis Virus in complex with the single domain antibody V2C3
Cryo ET of Native Hippocampal Glutamatergic Synapses without AuNP label 4
Cryo ET of Native Hippocampal Glutamatergic Synapses without AuNP label 2
Cryo ET of Native Hippocampal Glutamatergic Synapses Using Dimeric AuNP Labeling 3
TMD focus refined map of Non-active state Gly/Glu/PS bound hGluN1a-2B NMDAR
ECD focus refined map of Closed state Gly/Glu/24S-HC bound hGluN1a-2B NMDAR
Consensus map of pre-active state Gly/Glu/PS bound hGluN1a-2B NMDAR
ECD focus refined map of preactive state Gly/Glu/PS bound hGluN1a-2B NMDAR
TMD focus refined Closed state Gly/Glu/24S-HC bound hGluN1a-2B NMDAR
Consensus map of Non-active state Gly/Glu/PS bound hGluN1a-2B NMDAR
TMD focused refined open state Gly/Glu/24S-HC bound hGluN1a-2B NMDAR
TMD focus refined map of preactive state Gly/Glu/PS bound hGluN1a-2B NMDAR
Consensus map of open state Gly/Glu/24S-HC bound hGluN1a-2B NMDAR
Structure of HTTQ23-HAP40 complex bound to a small molecule ligand
CryoEM structure of H7 hemagglutinin in complex with a human neutralizing antibody 6Y13
Local map of Cryo-EM Structure of NPFFR1 in complex with peptide NPFF
Consensus map of Cryo-EM Structure of NPFFR1 in complex with peptide RFRP-3
Cryo-EM structure of bicarbonate transporter SbtA in complex with PII-like signaling protein SbtB (T-loop truncation) from Synechocystis sp. PCC 6803
Local map of Cryo-EM Structure of NPFFR1 in complex with peptide RFRP-3
Consensus map of Cryo-EM Structure of NPFFR1 in complex with peptide NPFF
Cryo-EM structure of the TIA-1 prion-like domain amyloid fibril, G355R
Cryo-EM structure of the TIA-1 prion-like domain amyloid fibril, WT
Cryo-EM structure of hTUT4_mini:hLin28A:pre-let-7g miRNA_UUU, conformation 2
Cryo-EM structure of hTUT4_mini:hLin28A:pre-let-7g miRNA_UUU, conformation 1
In situ cryo-ET tomogram of HeLa TMEM192-3xHA Control cell showcasing an endolysosomal structure.
In situ cryo-ET tomogram of HeLa TMEM192-3xHA ASAH1-/- cell showcasing an endolysosomal structure