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E. coli SIR2-HerA complex (hexamer HerA bound with dodecamer Sir2)
Resolution: 2.83 Å
EM Method: Single-particle
Fitted PDBs: 8su9
Q-score: 0.562
Shen Z, Lin Q, Yang XY, Fosuah E, Fu TM
Mol Cell (2023) 83 pp. 4586-4599.e5 [ Pubmed: 38096827 DOI: doi:10.1016/j.molcel.2023.11.007 ]
- Sir2-like domain-containing protein (46 kDa, Protein from Escherichia coli)
- Magnesium ion (24 Da, Ligand)
- E. coli sir2-hera complex (Complex from Escherichia coli)
- [(2r,3s,4r,5r)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl [hydroxy-[[(2r,3s,4r,5s)-3,4,5-trihydroxyoxolan-2-yl]methoxy]phosphoryl] hydrogen phosphate (559 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Nucleoside triphosphate hydrolase (68 kDa, Protein from Escherichia coli)
E. coli SIR2-HerA complex (dodecamer SIR2 bound 4 protomers of HerA)
Resolution: 3.15 Å
EM Method: Single-particle
Fitted PDBs: 8suw
Q-score: 0.439
Shen Z, Lin Q, Yang XY, Fosuah E, Fu TM
Mol Cell (2023) 83 pp. 4586-4599.e5 [ Pubmed: 38096827 DOI: doi:10.1016/j.molcel.2023.11.007 ]
- Sir2-like domain-containing protein (46 kDa, Protein from Escherichia coli)
- Sir2-hera complex(dodecomaer sir2 bound with four protomers of hera) (Complex from Escherichia coli)
- Magnesium ion (24 Da, Ligand)
- [(2r,3s,4r,5r)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl [hydroxy-[[(2r,3s,4r,5s)-3,4,5-trihydroxyoxolan-2-yl]methoxy]phosphoryl] hydrogen phosphate (559 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Nucleoside triphosphate hydrolase (68 kDa, Protein from Escherichia coli)
Structure of E. coli PtuA hexamer
Resolution: 2.93 Å
EM Method: Single-particle
Fitted PDBs: 8sux
Q-score: 0.5
Li Y, Shen Z, Zhang M, Yang XY, Cleary SP, Xie J, Marathe IA, Kostelic M, Greenwald J, Rish AD, Wysocki VH, Chen C, Chen Q, Fu TM, Yu Y
Nat Struct Mol Biol (2024) 31 pp. 413-423 [ DOI: doi:10.1038/s41594-023-01172-8 Pubmed: 38177683 ]
- Ptua (53 kDa, Protein from Escherichia coli)
- Ptua (Complex from Escherichia coli)
- Adenosine-5'-triphosphate (507 Da, Ligand)
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8ee4
Q-score: 0.576
Li Y, Shen Z, Zhang M, Yang XY, Cleary SP, Xie J, Marathe IA, Kostelic M, Greenwald J, Rish AD, Wysocki VH, Chen C, Chen Q, Fu TM, Yu Y
Nat Struct Mol Biol (2024) 31 pp. 413-423 [ DOI: doi:10.1038/s41594-023-01172-8 Pubmed: 38177683 ]
- Ptua (53 kDa, Protein from Escherichia coli)
- 6 ptua form as a complex (Complex from Escherichia coli)
- Adenosine-5'-triphosphate (507 Da, Ligand)
Structure of focused PtuA(dimer) and PtuB(monomer) complex
Resolution: 2.72 Å
EM Method: Single-particle
Fitted PDBs: 8ee7
Q-score: 0.609
Li Y, Shen Z, Zhang M, Yang XY, Cleary SP, Xie J, Marathe IA, Kostelic M, Greenwald J, Rish AD, Wysocki VH, Chen C, Chen Q, Fu TM, Yu Y
Nat Struct Mol Biol (2024) 31 pp. 413-423 [ DOI: doi:10.1038/s41594-023-01172-8 Pubmed: 38177683 ]
- Ptua (53 kDa, Protein from Escherichia coli)
- 6 ptua form as a complex (Complex from Escherichia coli)
- Ptub (28 kDa, Protein from Escherichia coli)
- Adenosine-5'-triphosphate (507 Da, Ligand)
Structure of E.coli Septu (PtuAB) complex
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8eea
Q-score: 0.603
Li Y, Shen Z, Zhang M, Yang XY, Cleary SP, Xie J, Marathe IA, Kostelic M, Greenwald J, Rish AD, Wysocki VH, Chen C, Chen Q, Fu TM, Yu Y
Nat Struct Mol Biol (2024) 31 pp. 413-423 [ DOI: doi:10.1038/s41594-023-01172-8 Pubmed: 38177683 ]
- Ptua (53 kDa, Protein from Escherichia coli)
- Ptub (28 kDa, Protein from Escherichia coli)
- 6 ptua and 2 ptub form as a complex (Complex from Escherichia coli)
- Adenosine-5'-triphosphate (507 Da, Ligand)
E. coli SIR2-HerA complex (dodecamer SIR2 pentamer HerA)
Resolution: 2.89 Å
EM Method: Single-particle
Fitted PDBs: 8sub
Q-score: 0.515
Shen Z, Lin Q, Yang XY, Fosuah E, Fu TM
Mol Cell (2023) 83 pp. 4586-4599.e5 [ Pubmed: 38096827 DOI: doi:10.1016/j.molcel.2023.11.007 ]
- Sir2-like domain-containing protein (46 kDa, Protein from Escherichia coli)
- Sir2-hera complex 2(12:5) (Complex from Escherichia coli)
- Magnesium ion (24 Da, Ligand)
- [(2r,3s,4r,5r)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl [hydroxy-[[(2r,3s,4r,5s)-3,4,5-trihydroxyoxolan-2-yl]methoxy]phosphoryl] hydrogen phosphate (559 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Nucleoside triphosphate hydrolase (68 kDa, Protein from Escherichia coli)
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8sxx
Q-score: 0.2
Shen Z, Lin Q, Yang XY, Fosuah E, Fu TM
Mol Cell (2023) 83 pp. 4586-4599.e5 [ Pubmed: 38096827 DOI: doi:10.1016/j.molcel.2023.11.007 ]
- Sir2-like domain-containing protein (46 kDa, Protein from Escherichia coli)
- E. coli dodecamer sir2 (Complex from Escherichia coli)
- Nicotinamide-adenine-dinucleotide (663 Da, Ligand)
E. coli Sir2_HerA complex (12:6) with ATPgamaS
Resolution: 3.25 Å
EM Method: Single-particle
Fitted PDBs: 8uae
Q-score: 0.492
Shen Z, Lin Q, Yang XY, Fosuah E, Fu TM
Mol Cell (2023) 83 pp. 4586-4599.e5 [ Pubmed: 38096827 DOI: doi:10.1016/j.molcel.2023.11.007 ]
- Phosphothiophosphoric acid-adenylate ester (523 Da, Ligand)
- Sir2-like domain-containing protein (46 kDa, Protein from Escherichia coli)
- Sir2_hera complex (12:6) with atpgamas (Complex from Escherichia coli)
- Magnesium ion (24 Da, Ligand)
- [(2r,3s,4r,5r)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl [hydroxy-[[(2r,3s,4r,5s)-3,4,5-trihydroxyoxolan-2-yl]methoxy]phosphoryl] hydrogen phosphate (559 Da, Ligand)
- Nucleoside triphosphate hydrolase (68 kDa, Protein from Escherichia coli)
E. coli Sir2_HerA complex (12:6) bound with NAD+
Resolution: 3.18 Å
EM Method: Single-particle
Fitted PDBs: 8uaf
Q-score: 0.393
Shen Z, Lin Q, Yang XY, Fosuah E, Fu TM
Mol Cell (2023) 83 pp. 4586-4599.e5 [ Pubmed: 38096827 DOI: doi:10.1016/j.molcel.2023.11.007 ]
- Nicotinamide-adenine-dinucleotide (663 Da, Ligand)
- Sir2-like domain-containing protein (46 kDa, Protein from Escherichia coli)
- Hera-sir2 complex bound with nad+ (Complex from Escherichia coli)
- Magnesium ion (24 Da, Ligand)
- [(2r,3s,4r,5r)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl [hydroxy-[[(2r,3s,4r,5s)-3,4,5-trihydroxyoxolan-2-yl]methoxy]phosphoryl] hydrogen phosphate (559 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Nucleoside triphosphate hydrolase (68 kDa, Protein from Escherichia coli)