CHEBI:67337 - Dolastatin 16

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ChEBI Name Dolastatin 16
ChEBI ID CHEBI:67337
Definition A natural product found particularly in Lyngbya majuscula and Dolabella auricularia.
Stars This entity has been manually annotated by a third party.
Supplier Information
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Formula C47H70N6O10
Net Charge 0
Average Mass 879.09290
Monoisotopic Mass 878.51534
InChI InChI=1S/C47H70N6O10/c1-26(2)36-30(8)46(60)62-31(9)42(56)53-24-16-21-35(53)47(61)63-39(28(5)6)45(59)50(10)38(27(3)4)44(58)52-23-15-20-34(52)41(55)49-37(29(7)25-32-17-12-11-13-18-32)43(57)51-22-14-19-33(51)40(54)48-36/h11-13,17-18,26-31,33-39H,14-16,19-25H2,1-10H3,(H,48,54)(H,49,55)/t29-,30-,31+,33+,34+,35+,36-,37+,38-,39-/m1/s1
InChIKey JXOFEBNJOOEXJY-QNCIAAGJSA-N
SMILES CC(C)[C@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@@H](NC(=O)[C@@H]2CCCN2C(=O)[C@@H](C(C)C)N(C)C(=O)[C@H](OC(=O)[C@@H]2CCCN2C(=O)[C@H](C)OC(=O)[C@@H]1C)C(C)C)[C@H](C)Cc1ccccc1
Metabolite of Species Details
Lyngbya majuscula (NCBI:txid158786) See: PubMed
Symploca hydnoides (NCBI:txid207924) EtOAc-MeOH(1:1) extract of freeze-dried cyanobacteria See: PubMed
Dolabella auricularia (NCBI:txid6511) See: PubMed
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing Dolastatin 16 (CHEBI:67337) has role metabolite (CHEBI:25212)
Dolastatin 16 (CHEBI:67337) is a cyclodepsipeptide (CHEBI:35213)
Synonym Source
7-epi-3,4-bis-nor-dolastatin 11 ChEBI
Manual Xref Database
0192214576 ChemIDplus
View more database links
Citations Waiting for Citations Types Sources
21446699 PubMed citation Europe PMC
21539315 PubMed citation Europe PMC
Last Modified
22 September 2014
General Comment
2014-10-17 Suggested Classification: ISA:macrolide(CHEBI:25106); ISA:lactam(CHEBI:24995); ISA:keratan 6'-sulfate(CHEBI:18331); ISA:azamacrocycle(CHEBI:52898); ISA:alpha-amino acid ester(CHEBI:46874); ISA:alkylbenzene(CHEBI:38976); ISA:aralkylamine(CHEBI:18000); ISA:dicarboxylic acid(CHEBI:35692); ISA:carboxamide(CHEBI:37622); ISA:pyrrolidines(CHEBI:38260); ISA:tertiary amine(CHEBI:32876); ISA:carboxylic ester(CHEBI:33308); ISA:lactone(CHEBI:25000); ISA:carboxylic acid(CHEBI:33575); ISA:ether(CHEBI:25698); ISA:carbonyl compound(CHEBI:36586);