CHEBI:31568 - profenamine hydrochloride

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ChEBI Name profenamine hydrochloride
ChEBI ID CHEBI:31568
Definition The monohydrochloride salt of profenamine. An antimuscarinic, it is used for the symptomatic treatment of Parkinson's disease.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C19H25ClN2S
Net Charge 0
Average Mass 348.93300
Monoisotopic Mass 348.14270
InChI InChI=1S/C19H24N2S.ClH/c1-4-20(5-2)15(3)14-21-16-10-6-8-12-18(16)22-19-13-9-7-11-17(19)21;/h6-13,15H,4-5,14H2,1-3H3;1H
InChIKey VXPCQISYVPFYRK-UHFFFAOYSA-N
SMILES Cl.CCN(CC)C(C)CN1c2ccccc2Sc2ccccc12
Roles Classification
Biological Role(s): adrenergic antagonist
An agent that binds to but does not activate adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists.
histamine antagonist
Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists.
muscarinic antagonist
A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
Application(s): adrenergic antagonist
An agent that binds to but does not activate adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists.
histamine antagonist
Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists.
antiparkinson drug
A drug used in the treatment of Parkinson's disease.
muscarinic antagonist
A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing profenamine hydrochloride (CHEBI:31568) has part profenamine (CHEBI:313639)
profenamine hydrochloride (CHEBI:31568) has role adrenergic antagonist (CHEBI:37887)
profenamine hydrochloride (CHEBI:31568) has role antiparkinson drug (CHEBI:48407)
profenamine hydrochloride (CHEBI:31568) has role histamine antagonist (CHEBI:37956)
profenamine hydrochloride (CHEBI:31568) has role muscarinic antagonist (CHEBI:48876)
profenamine hydrochloride (CHEBI:31568) is a hydrochloride (CHEBI:36807)
IUPAC Name
N,N-diethyl-1-(10H-phenothiazin-10-yl)propan-2-amine hydrochloride
Synonyms Sources
10-(2-(diethylamino)propyl)phenothiazine monohydrochloride ChemIDplus
ethopropazine HCl ChemIDplus
ethopropazine hydrochloride ChemIDplus
ethopropazine monohydrochloride ChEBI
N,N-diethyl-α-methyl-10H-phenothiazine-10-ethylamine hydrochloride ChEBI
N,N-diethyl-α-methyl-10H-phenothiazine-10-ethylamine monohydrochloride ChemIDplus
profenamine HCl ChEBI
profenamine monohydrochloride ChemIDplus
Manual Xrefs Databases
D01118 KEGG DRUG
DB00392 DrugBank
View more database links
Registry Numbers Types Sources
1094-08-2 CAS Registry Number ChemIDplus
1094-08-2 CAS Registry Number KEGG DRUG
Citations Waiting for Citations Types Sources
12200839 PubMed citation Europe PMC
13042233 PubMed citation Europe PMC
29438107 PubMed citation Europe PMC
Last Modified
14 June 2018