CHEBI:6722 - megestrol

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ChEBI Name megestrol ChEBI ID CHEBI:6722 Definition A 3-oxo Δ4-steroid that is pregna-4,6-diene-3,20-dione substituted by a methyl group at position 6 and a hydroxy group at position 17. Stars This entity has been manually annotated by the ChEBI Team. Supplier Information Download Molfile XML SDF Find compounds which contain this structure Find compounds which resemble this structure Take structure to the Advanced Search Wikipedia License Read full article at Wikipedia Formula C22H30O3 Net Charge 0 Average Mass 328.44522 Monoisotopic Mass 328.20384 InChI InChI=1S/C22H30O3/c1-13-11-16-17(20(3)8-5-15(24)12-19(13)20)6-9-21(4)18(16)7-10-22(21,25)14(2)23/h11-12,16-18,25H,5-10H2,1-4H3/t16-,17+,18+,20-,21+,22+/m1/s1 InChIKey VXIMPSPISRVBPZ-NWUMPJBXSA-N SMILES [H][C@@]12CC[C@](O)(C(C)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])C=C(C)C2=CC(=O)CC[C@]12C Roles Classification Biological Role(s): progestin A synthetic progestogen. Application(s): contraceptive drug A chemical substance that prevents or reduces the probability of conception. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. appetite enhancer A drug which increases appetite. synthetic oral contraceptive An oral contraceptive which owes its effectiveness to synthetic preparation. View more via ChEBI Ontology ChEBI Ontology Outgoing megestrol (CHEBI:6722) has role antineoplastic agent (CHEBI:35610) megestrol (CHEBI:6722) has role appetite enhancer (CHEBI:50779) megestrol (CHEBI:6722) has role contraceptive drug (CHEBI:49323) megestrol (CHEBI:6722) has role progestin (CHEBI:59826) megestrol (CHEBI:6722) has role synthetic oral contraceptive (CHEBI:49326) megestrol (CHEBI:6722) is a 17α-hydroxy steroid (CHEBI:35342) megestrol (CHEBI:6722) is a 20-oxo steroid (CHEBI:36885) megestrol (CHEBI:6722) is a 3-oxo-Δ4 steroid (CHEBI:47909) megestrol (CHEBI:6722) is a tertiary α-hydroxy ketone (CHEBI:139592) Incoming megestrol acetate (CHEBI:6723) has functional parent megestrol (CHEBI:6722) IUPAC Name 17-hydroxy-6-methylpregna-4,6-diene-3,20-dione INNs Sources mégestrol ChEBI megestrol ChEBI megestrolum ChEBI Synonyms Sources 17-Hydroxy-6-methylpregna-4,6-diene-3,20-dione ChemIDplus Megestrol KEGG COMPOUND megestrolo ChemIDplus Brand Names Sources Magestin DrugBank Megeron DrugBank Niagestin DrugBank Ovaban DrugBank Ovarid DrugBank Volidan DrugBank Manual Xrefs Databases C07120 KEGG COMPOUND D08167 KEGG DRUG DB00351 DrugBank HMDB0014495 HMDB LMST02030177 LIPID MAPS Megestrol Wikipedia View more database links Registry Numbers Types Sources 3164843 Reaxys Registry Number Reaxys 3562-63-8 CAS Registry Number ChemIDplus Citations Types Sources 12161003 PubMed citation Europe PMC 32037291 PubMed citation Europe PMC 32047089 PubMed citation Europe PMC 32352735 PubMed citation Europe PMC 32644631 PubMed citation Europe PMC 32652300 PubMed citation Europe PMC Last Modified 02 October 2020