CHEBI:91076 - PD-153035

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ChEBI Name PD-153035
ChEBI ID CHEBI:91076
Definition A member of the class of quinazolines carrying a 3-bromophenylamino substituent at position 4 and two methoxy substituents at positions 6 and 7.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C16H14BrN3O2
Net Charge 0
Average Mass 360.205
Monoisotopic Mass 359.02694
InChI InChI=1S/C16H14BrN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20)
InChIKey LSPANGZZENHZNJ-UHFFFAOYSA-N
SMILES N1=C2C(=C(N=C1)NC3=CC=CC(=C3)Br)C=C(C(=C2)OC)OC
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
An EC 2.7.10.* (protein-tyrosine kinase) inhibitor that interferes with the action of receptor protein-tyrosine kinase (EC 2.7.10.1).
epidermal growth factor receptor antagonist
An antagonist at the epidermal growth factor receptor.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing PD-153035 (CHEBI:91076) has role EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor (CHEBI:62434)
PD-153035 (CHEBI:91076) has role epidermal growth factor receptor antagonist (CHEBI:74440)
PD-153035 (CHEBI:91076) is a aromatic amine (CHEBI:33860)
PD-153035 (CHEBI:91076) is a aromatic ether (CHEBI:35618)
PD-153035 (CHEBI:91076) is a bromobenzenes (CHEBI:37149)
PD-153035 (CHEBI:91076) is a quinazolines (CHEBI:38530)
PD-153035 (CHEBI:91076) is a secondary amino compound (CHEBI:50995)
PD-153035 (CHEBI:91076) is conjugate base of PD-153035(1+) (CHEBI:91077)
Incoming PD-153035(1+) (CHEBI:91077) is conjugate acid of PD-153035 (CHEBI:91076)
IUPAC Name
N-(3-bromophenyl)-6,7-dimethoxyquinazolin-4-amine
Synonyms Sources
(3-Bromophenyl)(6,7-dimethoxyquinazolin-4-yl)amine ChemIDplus
4-(3-Bromophenylamino)-6,7-dimethoxyquinazoline ChemIDplus
AG-1517 ChemIDplus
NSC-669364 ChemIDplus
PD 153035 ChEBI
PD153035 ChEBI
SU-5271 ChemIDplus
Registry Numbers Types Sources
153436-54-5 CAS Registry Number ChemIDplus
7384032 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
23765435 PubMed citation Europe PMC
26125777 PubMed citation Europe PMC
26334931 PubMed citation Europe PMC
26464147 PubMed citation Europe PMC
Last Modified
03 February 2016