fenoprofen calcium (CHEBI:5005)

ChEBI > Main

Main

ChEBI Ontology

Automatic Xrefs

Reactions

Pathways

Models

ChEBI Name	fenoprofen calcium

ChEBI ID	CHEBI:5005

Definition	The dihydrate form of the calcium salt of fenoprofen. A non-steroidal anti-inflammatory drug, it is used for the management of mild to moderate pain and for the relief of pain and inflammation associated with disorders such as arthritis. It is pharmacologically similar to aspirin, but causes less gastrointestinal bleeding.

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

Download	Molfile XML SDF

Formula

C30H30CaO8

Net Charge

Average Mass

558.63200

Monoisotopic Mass

558.15666

InChI

InChI=1S/2C15H14O3.Ca.2H2O/c2*1-11(15(16)17)12-6-5-9-14(10-12)18-13-7-3-2-4-8-13;;;/h2*2-11H,1H3,(H,16,17);;2*1H2/q;;+2;;/p-2

InChIKey

LZPBLUATTGKZBH-UHFFFAOYSA-L

SMILES

O.O.[Ca++].CC(C([O-])=O)c1cccc(Oc2ccccc2)c1.CC(C([O-])=O)c1cccc(Oc2ccccc2)c1

Roles Classification
Biological Role(s):	cyclooxygenase 2 inhibitor A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 2. cyclooxygenase 1 inhibitor A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 1. non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.

Application(s):	non-steroidal anti-inflammatory drug An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. antipyretic A drug that prevents or reduces fever by lowering the body temperature from a raised state. An antipyretic will not affect the normal body temperature if one does not have fever. Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever. non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.

ChEBI Ontology
Outgoing	fenoprofen calcium (CHEBI:5005) has part fenoprofen calcium (anhydrous) (CHEBI:5010) fenoprofen calcium (CHEBI:5005) has role antipyretic (CHEBI:35493) fenoprofen calcium (CHEBI:5005) has role cyclooxygenase 1 inhibitor (CHEBI:50630) fenoprofen calcium (CHEBI:5005) has role cyclooxygenase 2 inhibitor (CHEBI:50629) fenoprofen calcium (CHEBI:5005) has role non-narcotic analgesic (CHEBI:35481) fenoprofen calcium (CHEBI:5005) has role non-steroidal anti-inflammatory drug (CHEBI:35475) fenoprofen calcium (CHEBI:5005) is a hydrate (CHEBI:35505)

INN	Source
fenoprofen calcium	ChEBI

Synonyms	Sources
(±)-α-methyl-3-phenoxybenzeneacetic acid calcium salt dihydrate	ChemIDplus
calcium (±)--phenoxyhydratropate dihydrate	ChemIDplus
calcium (±)-2-(3-phenoxyphenyl)propionate dihydrate	ChEBI
calcium 2-(3-phenoxyphenyl)propionate dihydrate	ChEBI
calcium 2-(m-phenoxyphenyl)propionate dihydrate	ChEBI
calcium α-(m-phenoxyphenyl)propionate dihydrate	ChEBI
calcium α-methyl-3-phenoxybenzeneacetate dihydrate	ChEBI
fenoprofen calcium 2H₂O	ChEBI
fenoprofen calcium dihydrate	ChemIDplus
fenoprofen calcium hydrate	DrugBank
fenoprofen calcium salt dihydrate	ChemIDplus

Last Modified

19 November 2010