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anthramycin |
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CHEBI:40699 |
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A member of the class of pyrrolobenzodiazepines that is (11aS)-5,10,11,11a-tetrahydro-1H-pyrrolo[2,1-c][1,4]benzodiazepine substituted at positions 2, 5, 8, 9 and 11R by a (1E)-3-amino-3-oxoprop-1-en-1-yl, oxo, methyl, hydroxy and hydroxy groups, respectively. It is a natural product isolated from Streptomyces refuineus subsp. thermotolerans. |
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This entity has been manually annotated by the ChEBI Team.
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Molfile
XML
SDF
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more structures >>
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InChI=1S/C16H17N3O4/c1-8-2-4-10-13(14(8)21)18-15(22)11-6-9(3-5-12(17)20)7-19(11)16(10)23/h2-5,7,11,15,18,21-22H,6H2,1H3,(H2,17,20)/b5-3+/t11-,15+/m0/s1 |
VGQOVCHZGQWAOI-YQRHFANHSA-N |
[H][C@@]12CC(\C=C\C(N)=O)=CN1C(=O)C1=C(N[C@@H]2O)C(O)=C(C)C=C1 |
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Streptomyces refuineus subsp. thermotolerans
(NCBI:txid223297)
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See:
PubMed
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bacterial metabolite
Any prokaryotic metabolite produced during a metabolic reaction in bacteria.
alkylating agent
Highly reactive chemical that introduces alkyl radicals into biologically active molecules and thereby prevents their proper functioning. It could be used as an antineoplastic agent, but it might be very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. It could also be used as a component of poison gases.
toxin
Poisonous substance produced by a biological organism such as a microbe, animal or plant.
antibacterial agent
A substance (or active part thereof) that kills or slows the growth of bacteria.
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antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
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View more via ChEBI Ontology
(2E)-3-[(11R,11aS)-9,11-dihydroxy-8-methyl-5-oxo-5,10,11,11a-tetrahydro-1H-pyrrolo[2,1-c][1,4]benzodiazepin-2-yl]prop-2-enamide
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antramicina
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WHO MedNet
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antramycin
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WHO MedNet
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antramycine
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WHO MedNet
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antramycinum
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WHO MedNet
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anthramycin
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ChemIDplus
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Ro 5-9000
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ChemIDplus
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4803-27-4
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CAS Registry Number
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ChemIDplus
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15599
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