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InChI=1S/CH4O/c1-2/h2H,1H3
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> Main
CHEBI:9287 - streptonigrin
Main
ChEBI Ontology
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ChEBI Name
streptonigrin
ChEBI ID
CHEBI:9287
Definition
Complex cytotoxic antibiotic obtained from
Streptomyces flocculus
or
S. rufochronmogenus
. It is used in advanced carcinoma and causes leukopenia.
Stars
This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs
CHEBI:108632
Supplier Information
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SDF
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Formula
C25H22N4O8
Net Charge
0
Average Mass
506.46420
Monoisotopic Mass
506.14376
InChI
InChI=1S/C25H22N4O8/c1-
9-
14(10-
6-
8-
13(35-
2)
23(36-
3)
20(10)
30)
15(26)
19(29-
17(9)
25(33)
34)
12-
7-
5-
11-
18(28-
12)
22(32)
16(27)
24(37-
4)
21(11)
31/h5-
8,30H,26-
27H2,1-
4H3,(H,33,34)
InChIKey
PVYJZLYGTZKPJE-UHFFFAOYSA-N
SMILES
COc1ccc(c(O)c1OC)-c1c(C)c(nc(c1N)-c1ccc2C(=O)C(OC)=C(N)C(=O)c2n1)C(O)=O
Roles Classification
Biological Role
(s):
antimicrobial agent
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
Application
(s):
antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing
streptonigrin (
CHEBI:9287
)
has role
antimicrobial agent (
CHEBI:33281
)
streptonigrin (
CHEBI:9287
)
has role
antineoplastic agent (
CHEBI:35610
)
streptonigrin (
CHEBI:9287
)
is a
pyridines (
CHEBI:26421
)
streptonigrin (
CHEBI:9287
)
is a
quinolone (
CHEBI:23765
)
IUPAC Name
5-
amino-
6-
(7-
amino-
6-
methoxy-
5,8-
dioxo-
5,8-
dihydroquinolin-
2-
yl)-
4-
(2-
hydroxy-
3,4-
dimethoxyphenyl)-
3-
methylpyridine-
2-
carboxylic acid
INNs
Sources
rufocromomicina
ChemIDplus
rufocromomycin
KEGG DRUG
rufocromomycine
ChemIDplus
rufocromomycinum
ChemIDplus
Synonyms
Sources
5-
Amino-
6-
(7-
amino-
5,8-
dihydro-
6-
methoxy-
5,8-
dioxo-
2-
quinolyl)-
4-
(2-
hydroxy-
3,4-
dimethoxyphenyl)-
3-
methylpicolinic acid
ChemIDplus
Streptonigran
ChemIDplus
Manual Xrefs
Databases
C00026485
KNApSAcK
C02081
KEGG COMPOUND
D05931
KEGG DRUG
View more database links
Registry Numbers
Types
Sources
1240693
Gmelin Registry Number
Gmelin
3930-19-6
CAS Registry Number
KEGG COMPOUND
3930-19-6
CAS Registry Number
ChemIDplus
599390
Beilstein Registry Number
Beilstein
Citations
Types
Sources
10328288
PubMed citation
ChEMBL
10465544
PubMed citation
ChEMBL
1905760
PubMed citation
ChEMBL
2738877
PubMed citation
ChEMBL
Last Modified
28 July 2014