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spiculoic acid A |
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CHEBI:66520 |
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A carbobicyclic compound that is 2,3,3a,4,5,7a-hexahydro-1H-indene substituted by ethyl groups at positions 3, 4, 5 and 7, a methyl group at position 1, an oxo group at position 2, a 2-phenylethenyl group at position 5 and a carboxy group at position 4 (the 1R,3R,3aS,4S,5R,7aS stereoisomer). Isolated from Plakortis angulospiculatus, it exhibits cytotoxicity against human breast cancer MCF-7 cells. |
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![](images/goldenstar.gif) ![](images/goldenstar.gif)
This entity has been manually annotated by the ChEBI Team.
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Molfile
XML
SDF
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InChI=1S/C27H36O3/c1- 6- 20- 17- 26(8- 3,16- 15- 19- 13- 11- 10- 12- 14- 19) 27(9- 4,25(29) 30) 23- 21(7- 2) 24(28) 18(5) 22(20) 23/h10- 18,21- 23H,6- 9H2,1- 5H3,(H,29,30) /b16- 15+/t18- ,21- ,22+,23- ,26- ,27- /m1/s1 |
ALLQJQBDLUMIQH-UOVLAWSHSA-N |
[H][C@@]12[C@@H](C)C(=O)[C@H](CC)[C@@]1([H])[C@](CC)(C(O)=O)[C@@](CC)(C=C2CC)\C=C\c1ccccc1 |
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Plakortis angulospiculatus
(NCBI:txid295227)
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See:
PubMed
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Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
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metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
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antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
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View more via ChEBI Ontology
(1R,3R,3aS,4S,5R,7aS)- 3,4,5,7- tetraethyl- 1- methyl- 2- oxo- 5- [(E)- 2- phenylethenyl]- 2,3,3a,4,5,7a- hexahydro- 1H- indene- 4- carboxylic acid
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9666648
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Reaxys Registry Number
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Reaxys
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14703354
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PubMed citation
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Europe PMC
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16320993
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PubMed citation
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Europe PMC
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17007398
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PubMed citation
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Europe PMC
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17107066
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PubMed citation
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Europe PMC
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22801647
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PubMed citation
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Europe PMC
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