CHEBI:180485 - amperozide hydrochloride

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ChEBI Name amperozide hydrochloride
ChEBI ID CHEBI:180485
Definition The hydrochloride salt of amperozide.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C23H29F2N3O.ClH
Net Charge 0
Average Mass 437.960
Monoisotopic Mass 437.20455
InChI InChI=1S/C23H29F2N3O.ClH/c1-2-26-23(29)28-16-14-27(15-17-28)13-3-4-22(18-5-9-20(24)10-6-18)19-7-11-21(25)12-8-19;/h5-12,22H,2-4,13-17H2,1H3,(H,26,29);1H
InChIKey OEQHKNWFXHBJIT-UHFFFAOYSA-N
SMILES Cl.CCNC(=O)N1CCN(CCCC(C2=CC=C(F)C=C2)C2=CC=C(F)C=C2)CC1
Roles Classification
Biological Role(s): dopamine uptake inhibitor
A dopaminergic agent that blocks the transport of dopamine into axon terminals or into storage vesicles within terminals. Most of the adrenergic uptake inhibitors also inhibit dopamine uptake.
serotonergic antagonist
Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.
Application(s): anxiolytic drug
Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions.
dopamine uptake inhibitor
A dopaminergic agent that blocks the transport of dopamine into axon terminals or into storage vesicles within terminals. Most of the adrenergic uptake inhibitors also inhibit dopamine uptake.
geroprotector
Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.
second generation antipsychotic
Antipsychotic drugs which can have different modes of action but which tend to be less likely than first generation antipsychotics to cause extrapyramidal motor control disabilities such as body rigidity or Parkinson's disease-type movements.
serotonergic antagonist
Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.
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ChEBI Ontology
Outgoing amperozide hydrochloride (CHEBI:180485) has part amperozide(1+) (CHEBI:180484)
amperozide hydrochloride (CHEBI:180485) has role anxiolytic drug (CHEBI:35474)
amperozide hydrochloride (CHEBI:180485) has role dopamine uptake inhibitor (CHEBI:51039)
amperozide hydrochloride (CHEBI:180485) has role geroprotector (CHEBI:176497)
amperozide hydrochloride (CHEBI:180485) has role second generation antipsychotic (CHEBI:65191)
amperozide hydrochloride (CHEBI:180485) has role serotonergic antagonist (CHEBI:48279)
amperozide hydrochloride (CHEBI:180485) is a hydrochloride (CHEBI:36807)
IUPAC Name
4-[4,4-bis(4-fluorophenyl)butyl]-N-ethylpiperazine-1-carboxamide hydrochloride
Synonyms Sources
1-[4,4-bis(4-fluorophenyl)butyl]-4-(ethylcarbamoyl)piperazin-1-ium chloride IUPAC
4-(4,4-bis(p-fluorophenyl)butyl)-N-ethyl-1-piperazinecarboxamide hydrochloride ChemIDplus
amperozide HCl ChemIDplus
amperozide monohydrochloride ChEBI
FG 5606 ChEBI
FG-5606 ChEBI
Brand Name Source
Hogpax ChemIDplus
Manual Xref Database
66063 ChemSpider
View more database links
Registry Numbers Types Sources
75529-73-6 CAS Registry Number ChemIDplus
86725-37-3 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
1388121 PubMed citation Europe PMC
24134630 PubMed citation Europe PMC
2572972 PubMed citation Europe PMC
2825928 PubMed citation Europe PMC
8332634 PubMed citation Europe PMC
Last Modified
20 September 2021