CHEBI:65648 - cochinchinone C

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ChEBI Name cochinchinone C
ChEBI ID CHEBI:65648
Definition A polycyclic cage that is a prenylated-caged xanthone isolated from Cratoxylum cochinchinense and has been shown to exhibit antimalarial and antioxidant activities.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C24H26O6
Net Charge 0
Average Mass 410.45960
Monoisotopic Mass 410.17294
InChI InChI=1S/C24H26O6/c1-13(2)9-10-23-20(27)22(28-5)11-14-19(26)18-15(25)7-6-8-16(18)29-24(14,23)17(12-22)21(3,4)30-23/h6-9,11,17,25H,10,12H2,1-5H3/t17-,22-,23-,24+/m0/s1
InChIKey XWFNYKWKDWAAMZ-OWYCYUENSA-N
SMILES [H][C@@]12C[C@@]3(OC)C=C4C(=O)c5c(O)cccc5O[C@@]14[C@@](CC=C(C)C)(OC2(C)C)C3=O
Metabolite of Species Details
Cratoxylum cochinchinense (NCBI:txid271749) Found in root (BTO:0001188). See: PubMed
Roles Classification
Chemical Role(s): antioxidant
A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides.
Biological Role(s): antimalarial
A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human.
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
Application(s): antimalarial
A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing cochinchinone C (CHEBI:65648) has role antimalarial (CHEBI:38068)
cochinchinone C (CHEBI:65648) has role antioxidant (CHEBI:22586)
cochinchinone C (CHEBI:65648) has role metabolite (CHEBI:25212)
cochinchinone C (CHEBI:65648) is a cyclic ether (CHEBI:37407)
cochinchinone C (CHEBI:65648) is a cyclic ketone (CHEBI:3992)
cochinchinone C (CHEBI:65648) is a phenols (CHEBI:33853)
cochinchinone C (CHEBI:65648) is a polycyclic cage (CHEBI:33640)
IUPAC Name
(1R,3aS,5R,12aS)-8-hydroxy-5-methoxy-3,3-dimethyl-1-(3-methylbut-2-en-1-yl)-3,3a,4,5-tetrahydro-7H-1,5-methanofuro[3,4-d]xanthene-7,13-dione
Registry Number Type Source
10389050 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
16310231 PubMed citation Europe PMC
16651783 PubMed citation Europe PMC
Last Modified
31 July 2013