CHEBI:135173 - taurolidine

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ChEBI Name taurolidine
ChEBI ID CHEBI:135173
Definition A member of the class of thiadiazinanes that is 1,2,4-thiadiazinane 1,1-dioxide substituted by a (1,1-dioxido-1,2,4-thiadiazinan-4-yl)methyl group at position 4. It is a broad-spectrum antiseptic used as lock therapy solution in patients with long term central venous catheters for the prevention of catheter related bloodstream infections.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C7H16N4O4S2
Net Charge 0
Average Mass 284.350
Monoisotopic Mass 284.06130
InChI InChI=1S/C7H16N4O4S2/c12-16(13)3-1-10(5-8-16)7-11-2-4-17(14,15)9-6-11/h8-9H,1-7H2
InChIKey AJKIRUJIDFJUKJ-UHFFFAOYSA-N
SMILES O=S1(=O)CCN(CN2CCS(=O)(=O)NC2)CN1
Roles Classification
Biological Role(s): antibacterial agent
A substance (or active part thereof) that kills or slows the growth of bacteria.
antifungal agent
An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce.
Application(s): anti-inflammatory agent
Any compound that has anti-inflammatory effects.
antiseptic drug
A substance used locally on humans and other animals to destroy harmful microorganisms or to inhibit their activity (cf. disinfectants, which destroy microorganisms found on non-living objects, and antibiotics, which can be transported through the lymphatic system to destroy bacteria within the body).
antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
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ChEBI Ontology
Outgoing taurolidine (CHEBI:135173) has role anti-inflammatory agent (CHEBI:67079)
taurolidine (CHEBI:135173) has role antibacterial agent (CHEBI:33282)
taurolidine (CHEBI:135173) has role antifungal agent (CHEBI:35718)
taurolidine (CHEBI:135173) has role antineoplastic agent (CHEBI:35610)
taurolidine (CHEBI:135173) has role antiseptic drug (CHEBI:48218)
taurolidine (CHEBI:135173) is a sulfone (CHEBI:35850)
taurolidine (CHEBI:135173) is a thiadiazinane (CHEBI:38781)
Incoming Defencath (CHEBI:230518) has part taurolidine (CHEBI:135173)
IUPAC Name
4,4'-methanediylbis(1,2,4-thiadiazinane) 1,1,1',1'-tetraoxide
INNs Sources
taurolidina WHO MedNet
taurolidine WHO MedNet
taurolidine WHO MedNet
taurolidinum WHO MedNet
Synonyms Sources
4,4'-methylenebis(1,2,4-thiadiazinane)-1,1,1',1'-tetraoxide ChEBI
4,4'-methylenebis(perhydro-1,2,4-thiadiazin 1,1-dioxide) ChEBI
4,4'-methylenedi(1λ6,2,4-thiadiazinane-1,1-dione) IUPAC
taurolin DrugCentral
tauroline DrugCentral
W-3100M DrugBank
Manual Xrefs Databases
2568 DrugCentral
D07146 KEGG DRUG
DB12473 DrugBank
HMDB0258744 HMDB
Taurolidine Wikipedia
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Registry Number Type Source
19388-87-5 CAS Registry Number KEGG DRUG
Citations Waiting for Citations Types Sources
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Last Modified
19 April 2024