SB 415286 (CHEBI:91107)

ChEBI > Main

Main

ChEBI Ontology

Automatic Xrefs

Reactions

Pathways

Models

ChEBI Name	SB 415286

ChEBI ID	CHEBI:91107

Definition	A member of the class of maleimides carrying 3-chloro-4-hydroxyphenylamino and 2-nitrophenyl substituents at positions 3 and 4 respectively.

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

Download	Molfile XML SDF

Formula

C16H10ClN3O5

Net Charge

Average Mass

359.721

Monoisotopic Mass

359.03090

InChI

InChI=1S/C16H10ClN3O5/c17-10-7-8(5-6-12(10)21)18-14-13(15(22)19-16(14)23)9-3-1-2-4-11(9)20(24)25/h1-7,21H,(H2,18,19,22,23)

InChIKey

PQCXVIPXISBFPN-UHFFFAOYSA-N

SMILES

N1C(C(=C(C1=O)NC2=CC=C(C(=C2)Cl)O)C3=CC=CC=C3[N+]([O-])=O)=O

Roles Classification
Chemical Role(s):	antioxidant A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. Bronsted base A molecular entity capable of accepting a hydron from a donor (Bronsted acid). (via organic amino compound )

Biological Role(s):	EC 2.7.11.26 (tau-protein kinase) inhibitor An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of tau-protein kinase inhibitor (EC 2.7.11.26). apoptosis inducer Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.

Application(s):	neuroprotective agent Any compound that can be used for the treatment of neurodegenerative disorders.

ChEBI Ontology
Outgoing	SB 415286 (CHEBI:91107) has role antioxidant (CHEBI:22586) SB 415286 (CHEBI:91107) has role apoptosis inducer (CHEBI:68495) SB 415286 (CHEBI:91107) has role EC 2.7.11.26 (tau-protein kinase) inhibitor (CHEBI:91092) SB 415286 (CHEBI:91107) has role neuroprotective agent (CHEBI:63726) SB 415286 (CHEBI:91107) is a C-nitro compound (CHEBI:35716) SB 415286 (CHEBI:91107) is a maleimides (CHEBI:55417) SB 415286 (CHEBI:91107) is a monochlorobenzenes (CHEBI:83403) SB 415286 (CHEBI:91107) is a phenols (CHEBI:33853) SB 415286 (CHEBI:91107) is a secondary amino compound (CHEBI:50995) SB 415286 (CHEBI:91107) is a substituted aniline (CHEBI:48975)

IUPAC Name

3-(3-chloro-4-hydroxyanilino)-4-(2-nitrophenyl)-1H-pyrrole-2,5-dione

Synonyms	Sources
3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione	ChemIDplus
SB-415286	ChemIDplus
SB415286	ChEBI

Last Modified

23 January 2023