CHEBI:147356 - tilorone dihydrochloride

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ChEBI Name tilorone dihydrochloride
ChEBI ID CHEBI:147356
Definition The dihydrochloride salt of tilorone. It is used as an antiviral drug to treat influenza, herpes infection, viral hepatitis, acute respiratory viral infections and SARS.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C25H34N2O3.ClH.ClH
Net Charge 0
Average Mass 483.470
Monoisotopic Mass 482.21030
InChI InChI=1S/C25H34N2O3.2ClH/c1-5-26(6-2)13-15-29-19-9-11-21-22-12-10-20(30-16-14-27(7-3)8-4)18-24(22)25(28)23(21)17-19;;/h9-12,17-18H,5-8,13-16H2,1-4H3;2*1H
InChIKey BSVYJQAWONIOOU-UHFFFAOYSA-N
SMILES C1=2C=3C(C(C1=CC(=CC2)OCCN(CC)CC)=O)=CC(=CC3)OCCN(CC)CC.Cl.Cl
Roles Classification
Biological Role(s): nicotinic acetylcholine receptor agonist
An agonist that selectively binds to and activates a nicotinic acetylcholine receptor.
antiviral drug
A substance used in the prophylaxis or therapy of virus diseases.
Application(s): anti-inflammatory agent
Any compound that has anti-inflammatory effects.
antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
interferon inducer
An agent that promotes the production and release of interferons.
nicotinic acetylcholine receptor agonist
An agonist that selectively binds to and activates a nicotinic acetylcholine receptor.
antiviral drug
A substance used in the prophylaxis or therapy of virus diseases.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing tilorone dihydrochloride (CHEBI:147356) has part tilorone(2+) (CHEBI:147355)
tilorone dihydrochloride (CHEBI:147356) has role anti-inflammatory agent (CHEBI:67079)
tilorone dihydrochloride (CHEBI:147356) has role antineoplastic agent (CHEBI:35610)
tilorone dihydrochloride (CHEBI:147356) has role antiviral drug (CHEBI:36044)
tilorone dihydrochloride (CHEBI:147356) has role interferon inducer (CHEBI:36710)
tilorone dihydrochloride (CHEBI:147356) has role nicotinic acetylcholine receptor agonist (CHEBI:47958)
tilorone dihydrochloride (CHEBI:147356) is a hydrochloride (CHEBI:36807)
IUPAC Name
2,7-bis[2-(diethylamino)ethoxy]-9H-fluoren-9-one dihydrochloride
Synonyms Sources
tilorone HCl ChemIDplus
tilorone hydrochloride ChemIDplus
Brand Names Sources
Amixin ChEBI
Lavomax ChEBI
Manual Xref Database
D06149 KEGG DRUG
View more database links
Registry Number Type Source
27591-69-1 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
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Last Modified
01 April 2020