Defencath (CHEBI:230518)

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ChEBI > Main

CHEBI:230518 - Defencath

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ChEBI Name	Defencath

ChEBI ID	CHEBI:230518

Definition	A mixture containing taurolidine (a thiadiazinane antimicrobial) and heparin sodium (an anti-coagulant). It is used to reduce the incidence of catheter-related bloodstream infections in adult patients with kidney failure receiving chronic hemodialysis through a central venous catheter.

Stars	This entity has been manually annotated by the ChEBI Team.

Wikipedia	License

Read full article at Wikipedia

Roles Classification
Biological Role(s):	antimicrobial agent A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.

Application(s):	antiinfective agent A substance used in the prophylaxis or therapy of infectious diseases. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. anticoagulant An agent that prevents blood clotting.

View more via ChEBI Ontology

ChEBI Ontology
Outgoing	Defencath (CHEBI:230518) has part heparin sodium (CHEBI:230519) Defencath (CHEBI:230518) has part taurolidine (CHEBI:135173) Defencath (CHEBI:230518) has role anticoagulant (CHEBI:50249) Defencath (CHEBI:230518) has role antiinfective agent (CHEBI:35441) Defencath (CHEBI:230518) has role antimicrobial agent (CHEBI:33281) Defencath (CHEBI:230518) has role antineoplastic agent (CHEBI:35610) Defencath (CHEBI:230518) is a mixture (CHEBI:60004)

Synonyms	Sources
taurolidine and heparin	KEGG DRUG
taurolidine, heparin	ChEBI
taurolidine/heparin	ChEBI

Brand Name	Source
Defencath	KEGG DRUG

Manual Xrefs	Databases
D12737	KEGG DRUG
Taurolidine/heparin	Wikipedia
View more database links

Citations	Types	Sources
10567800	PubMed citation	Europe PMC
11688959	PubMed citation	Europe PMC
12712383	PubMed citation	Europe PMC
14524527	PubMed citation	Europe PMC
17109891	PubMed citation	Europe PMC
17337889	PubMed citation	Europe PMC
17902020	PubMed citation	Europe PMC
22958287	PubMed citation	Europe PMC
29106676	PubMed citation	Europe PMC
29214504	PubMed citation	Europe PMC
34034903	PubMed citation	Europe PMC
36669952	PubMed citation	Europe PMC
37465871	PubMed citation	Europe PMC
37678222	PubMed citation	Europe PMC
38025316	PubMed citation	Europe PMC
38510847	PubMed citation	Europe PMC
9324156	PubMed citation	Europe PMC
9333705	PubMed citation	Europe PMC

Last Modified

19 April 2024