CHEBI:138645 - resolvin D5

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ChEBI Name resolvin D5
ChEBI ID CHEBI:138645
Definition A member of the class of resolvins that is (4Z,8E,10Z,13Z,15E,19Z)-docosahexaenoic acid carrying two hydroxy substituents at positions 7 and 17 (the 7S,17S-stereoisomer).
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Bijay
Supplier Information
Download Molfile XML SDF
Formula C22H32O4
Net Charge 0
Average Mass 360.494
Monoisotopic Mass 360.23006
InChI InChI=1S/C22H32O4/c1-2-3-10-15-20(23)16-11-7-5-4-6-8-12-17-21(24)18-13-9-14-19-22(25)26/h3,5-13,16-17,20-21,23-24H,2,4,14-15,18-19H2,1H3,(H,25,26)/b7-5-,8-6-,10-3-,13-9-,16-11+,17-12+/t20-,21+/m0/s1
InChIKey CFOFZYMMJZILHE-XGTWDWJNSA-N
SMILES CC\C=C/C[C@H](O)\C=C\C=C/C\C=C/C=C/[C@@H](O)C\C=C/CCC(O)=O
Metabolite of Species Details
Mus musculus (NCBI:txid10090) See: PubMed
Trypanosoma cruzi (NCBI:txid5693) See: PubMed
Oncorhynchus mykiss (NCBI:txid8022) See: PubMed
Homo sapiens (NCBI:txid9606) See: PubMed
Roles Classification
Chemical Role(s): Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Biological Role(s): human xenobiotic metabolite
Any human metabolite produced by metabolism of a xenobiotic compound in humans.
mouse metabolite
Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).
marine xenobiotic metabolite
Any metabolite produced by metabolism of a xenobiotic compound in marine macro- and microorganisms.
animal metabolite
Any eukaryotic metabolite produced during a metabolic reaction in animals that include diverse creatures from sponges, insects to mammals.
human metabolite
Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
specialised pro-resolving mediator
A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation.
(via resolvin )
Application(s): anti-inflammatory agent
Any compound that has anti-inflammatory effects.
platelet aggregation inhibitor
A drug or agent which antagonizes or impairs any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
specialised pro-resolving mediator
A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation.
(via resolvin )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing resolvin D5 (CHEBI:138645) has role animal metabolite (CHEBI:75767)
resolvin D5 (CHEBI:138645) has role anti-inflammatory agent (CHEBI:67079)
resolvin D5 (CHEBI:138645) has role human metabolite (CHEBI:77746)
resolvin D5 (CHEBI:138645) has role human xenobiotic metabolite (CHEBI:76967)
resolvin D5 (CHEBI:138645) has role marine xenobiotic metabolite (CHEBI:83399)
resolvin D5 (CHEBI:138645) has role mouse metabolite (CHEBI:75771)
resolvin D5 (CHEBI:138645) has role platelet aggregation inhibitor (CHEBI:50427)
resolvin D5 (CHEBI:138645) is a diol (CHEBI:23824)
resolvin D5 (CHEBI:138645) is a hydroxy polyunsaturated fatty acid (CHEBI:140345)
resolvin D5 (CHEBI:138645) is a resolvin (CHEBI:132120)
resolvin D5 (CHEBI:138645) is a secondary allylic alcohol (CHEBI:134396)
resolvin D5 (CHEBI:138645) is conjugate acid of resolvin D5(1−) (CHEBI:140352)
Incoming resolvin D5(1−) (CHEBI:140352) is conjugate base of resolvin D5 (CHEBI:138645)
IUPAC Name
(4Z,7S,8E,10Z,13Z,15E,17S,19Z)-7,17-dihydroxydocosa-4,8,10,13,15,19-hexaenoic acid
Synonyms Sources
(4Z,7S,8E,10Z,13Z,15E,17S,19Z)-7,17-dihydroxydocosahexaenoic acid ChEBI
7(S),17(S)-diHDHA ChEBI
7(S),17(S)-resolvin D5 ChEBI
7S,17S-diHDHA ChEBI
7S,17S-dihydroxy-4Z,8E,10Z,13Z,15E,19Z-docosahexaenoic acid ChEBI
resolvin-D5 ChEBI
RvD5 ChEBI
Manual Xrefs Databases
45743318 ChemSpider
FDB023286 FooDB
HMDB0004038 HMDB
LMFA04030003 LIPID MAPS
View more database links
Registry Number Type Source
578008-43-2 CAS Registry Number ChEBI
Citations Waiting for Citations Types Sources
16303609 PubMed citation Europe PMC
22538616 PubMed citation Europe PMC
22841830 PubMed citation Europe PMC
27320930 PubMed citation Europe PMC
27632672 PubMed citation Europe PMC
28098462 PubMed citation Europe PMC
28694292 PubMed citation Europe PMC
29358332 PubMed citation Europe PMC
31333464 PubMed citation Europe PMC
31693828 PubMed citation Europe PMC
32404334 PubMed citation Europe PMC
33047359 PubMed citation Europe PMC
PMC7257705 PubMed Central citation Europe PMC
Last Modified
25 May 2021