CHEBI:67174 - cortistatin C

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ChEBI Name cortistatin C
ChEBI ID CHEBI:67174
Definition A member of the class of cortistatins that is cortistatin A in which the hydrogens at position 16 have been replaced by an oxo group.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C30H34N2O4
Net Charge 0
Average Mass 486.60200
Monoisotopic Mass 486.25186
InChI InChI=1S/C30H34N2O4/c1-28-8-6-20-13-21-26(34)27(35)22(32(2)3)15-29(21)9-10-30(20,36-29)24(28)14-23(33)25(28)18-5-4-17-7-11-31-16-19(17)12-18/h4-7,11-13,16,22,24-27,34-35H,8-10,14-15H2,1-3H3/t22-,24+,25-,26+,27+,28-,29+,30+/m0/s1
InChIKey WMKCSKJMIPEVOG-HIGLSOHYSA-N
SMILES [H][C@@]12CC(=O)[C@H](c3ccc4ccncc4c3)[C@@]1(C)CC=C1C=C3[C@@H](O)[C@H](O)[C@H](C[C@]33CC[C@]21O3)N(C)C
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
(via alkaloid )
Application(s): angiogenesis modulating agent
An agent that modulates the physiologic angiogenesis process. This is accomplished by endogenous angiogenic proteins and a variety of other chemicals and pharmaceutical agents.
(via cortistatins )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing cortistatin C (CHEBI:67174) has functional parent cortistatin B (CHEBI:67173)
cortistatin C (CHEBI:67174) is a cortistatins (CHEBI:67169)
cortistatin C (CHEBI:67174) is a cyclic ketone (CHEBI:3992)
cortistatin C (CHEBI:67174) is a diol (CHEBI:23824)
cortistatin C (CHEBI:67174) is a secondary alcohol (CHEBI:35681)
Incoming cortistatin D (CHEBI:67175) has functional parent cortistatin C (CHEBI:67174)
IUPAC Name
(1R,2R,3S,5R)-3-(dimethylamino)-1,2-dihydroxy-17β-(isoquinolin-7-yl)-5,8α-epoxy-9,19-cyclo-9,10-secoandrosta-9(11),10-dien-16-one
Synonyms Sources
(−)-cortistatin C ChEBI
(1R,2R,3S,5R,8α,17β)-3-(dimethylamino)-1,2-dihydroxy-17-(isoquinolin-7-yl)-5,8-epoxy-9,19-cyclo-9,10-secoandrosta-9(11),10-dien-16-one IUPAC
Registry Number Type Source
10502498 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
16522087 PubMed citation Europe PMC
17765550 PubMed citation Europe PMC
Last Modified
21 August 2012